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UDP-Glucuronosyltransferase 2B17

Known as: UGT2B17, EC 2.4.1.17, UDP-Glucuronyltransferase, Family 2, Beta-17 
UDP-glucuronosyltransferase 2B17 (530 aa, ~61 kDa) is encoded by the human UGT2B17 gene. This protein plays a role in the metabolism of steroids and… 
National Institutes of Health

Related topics

Related topics

12 relations
Carbohydrate MetabolismEnzyme GeneGlycosyltransferase GenePentose and Glucuronate Interconversions Pathway

Papers overview

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2016
2016
UGT2B17 minor histocompatibility mismatch and clinical outcome after HLA-identical sibling donor stem cell transplantation
Minor histocompatibility Ags (mHags) have been implicated in the pathogenesis of GVHD after allogeneic hematopoietic stem cell… 
2011
2011
Impact of UDP-gluconoryltransferase 2B17 genotype on vorinostat metabolism and clinical outcomes in Asian women with breast cancer
Objectives Vorinostat, a histone deacetylase inhibitor being actively evaluated in solid tumors, is metabolized by UGT2B17… 
2011
2011
Epidemiological investigation of the UGT2B17 polymorphism in doping control urine samples and its correlation to T/E ratios.
The deletion polymorphism of the enzyme UGT2B17 is known to correlate with the level of the testosterone to epitestosterone (T/E… 
2009
2009
The Role of Human UDP-Glucuronyltransferases on the Formation of the Methylenedioxymethamphetamine (Ecstasy) Phase II Metabolites R- and S-3-Methoxymethamphetamine 4-O-Glucuronides
Different pharmacokinetic properties have been observed for the two enantiomers of the entactogen 3,4-methylendioxy… 
2009
2009
Comparative gene expression of intestinal metabolizing enzymes
The purpose of this study was to compare the expression profiles of drug‐metabolizing enzymes in the intestine of mouse, rat and… 
2006
2006
Chiral distinction between the enantiomers of bicyclic alcohols by UDP-glucuronosyltransferases 2B7 and 2B17
Abstract The stereoselective binding and transformation of optically pure bicyclic alcohols by human UDP-glucuronosyltransferases… 
1992
1992
Convenient synthesis of 18-hydroxylated cortisol and prednisolone
1985
1985
Steroids excreted by human skin. II. C19-steroid sulphates in human axillary sweat.
Beside dehydroepiandrosterone sulphate and androsterone sulphate, 5-androstene-3 beta, 17 beta-diol-3-sulphate and testosterone… 
1984
1984
Metabolism and concentration of androgenic steroids in the abdominal skin of women with idiopathic hirsutism.
The in vitro metabolisms of [4-14C]-labelled DHA, delta 5-diol, delta 4-dione and Test were studied in skin tissue excised from… 
1973
1973
Metabolism of androst-4-ene-3,17-dione by subcellular fractions of rat adrenal tissue with particular reference to microsomal C19-steroid 5alpha-reductase.
The location and some characteristics of rat adrenal C(19)-steroid 5alpha-reductase were investigated by using [7alpha-(3)H… 
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