UCS 1025A

UCS1025A is a fungal polyketide/alkaloid that displays strong inhibition of telomerase. The structures of UCS1025A and related… Expand

Microsatellite instability (MSI) contributes to the tumorigenesis of upper urinary tract urothelial carcinomas (UUT-UCs). In this… Expand

Whether or not laparoscopic nephroureterectomy (LNU) will play a key role in the future is the subject of ongoing debate. Open… Expand

BACKGROUND Urothelial carcinoma of the upper urinary tract (UUT-UC) was a rare, aggressive urologic cancer with a propensity for… Expand

Urinary catheters are widely used for hospitalized patients and are often associated with high rates of urinary tract infection… Expand

The flexibility consists in the motor capacity related with the amplitude of movement reached by each joint. The flexibility… Expand

The enantioselective total synthesis of the telomerase inhibitor UCS1025A has been accomplished. The key transformation involves… Expand

The mechanisms by which the excess genetic material of chromosome 21 results in the dysmorphologic features of Down syndrome (DS… Expand

OBJECTIVE To elucidate the role of various bcl-2 family molecules in the regulation of apoptosis and the progression of… Expand

Preconditioning experience with the unconditional stimulus (UCS) retards subsequent excitatory conditioning. Three experiments… Expand