UCS 1025A

Known as: UCS-1025A, UCS1025A 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2018
012320002018

Papers overview

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2018
2018
UCS1025A is a fungal polyketide/alkaloid that displays strong inhibition of telomerase. The structures of UCS1025A and related… (More)
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2012
2012
As part of our screening program to find new antitrypanosomal compounds, we evaluate isolates from soil-dwelling microorganisms… (More)
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Review
2008
Review
2008
There is an urgent need of novel approaches to drugs in the cancer, HIV, and bacterial areas. Increasing resistance to… (More)
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Review
2007
Review
2007
The current scope and limitations of organocatalytic reactions and the consequences for the strategic planning of natural product… (More)
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2006
2006
Telomerase has been proposed as a selective target for cancer chemotherapy. We established a forward chemical genetics approach… (More)
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2006
2006
The enantioselective total synthesis of the telomerase inhibitor UCS1025A has been accomplished. The key transformation involves… (More)
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2006
2006
A synthesis of the structurally fascinating fungal metabolite UCS1025A (1) was accomplished. It features a likely biomimetic… (More)
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2004
2004
Modified Moffat oxidation of alcohols 17, 22, and 25 afforded aldehydes that underwent intramolecular aldol reactions on… (More)
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2002
2002
[structure: see text] UCS1025A and B, novel pentacyclic polyketides with an unprecedented furopyrrolizidine skeleton, were… (More)
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2000
2000
antimicrobial activity, and antiproliferative activity against humantumor cell lines. In this paper, we describe the taxonomy of… (More)
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