UBA3 gene

Known as: NAE2, NEDD8-activating enzyme E1 catalytic subunit, hUba3 
This gene is involved in post-translational protein modification.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
024619922018

Papers overview

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2014
2014
The NEDD8-activating enzyme (NAE) initiates neddylation, the cascade of post-translational NEDD8 conjugation onto target proteins… (More)
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2013
2013
Protein expression abnormalities have been implicated in the pathophysiology of schizophrenia, but the underlying cause of these… (More)
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2012
2012
Inhibition of NEDD8-activating enzyme (NAE) has emerged as a highly promising approach to treat cancer through the adenosine… (More)
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2012
2012
Neural precursor cell-expressed developmentally down-regulated 8 (NEDD8), a ubiquitin-like protein, mainly functions through… (More)
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2008
2008
Post-translational covalent modification by ubiquitin and ubiquitin-like proteins (UBLs) is a major eukaryotic mechanism for… (More)
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2005
2005
The NEDD8 pathway is important for numerous biological processes, including cell proliferation, signal transduction, and… (More)
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2003
2003
We report here the localisation of BAIAP1 (13q24), HTR1F (13q45), PTPRG (13q23) and UBE1C (13q24) by fluorescence in situ… (More)
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Highly Cited
2000
Highly Cited
2000
APP-BP1 binds to the amyloid precursor protein (APP) carboxyl-terminal domain. Recent work suggests that APP-BP1 participates in… (More)
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Highly Cited
1999
Highly Cited
1999
NEDD8 is a ubiquitin-like molecule that can be covalently conjugated to a limited number of cellular proteins, such as Cdc53… (More)
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1992
1992
Ubiquitin-activating enzyme, E1, directs the ATP-dependent formation of a thiol ester linkage between itself and ubiquitin. The… (More)
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