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UACC-257

A melanoma cell line established from a patient with cutaneous melanoma.
National Institutes of Health

Papers overview

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2016
2016
Abstract 2809: ROS signaling by NADPH oxidase 5 (Nox5) modulates proliferation of human melanoma UACC-257 cells and prolongs growth in the absence of serum or growth factors
Reactive oxygen species (ROS) produced by the NADPH oxidase (Noxs) homologs participate in signaling cascades regulating… 
2015
2015
Synthesis of novel amides based on acridone scaffold with interesting antineoplastic activity.
In search of novel cytotoxic agents based on acridone scaffold, twenty five derivatives of acridone-2- carboxamide were… 
2013
2013
Structure elucidation of antiproliferative bisbenzylisoquinoline alkaloids from Anisocycla grandidieri from the Madagascar dry forest
Antiproliferative bioassay‐guided fractionation of the ethanol extract of the stems of Anisocycla grandidieri led to the… 
2013
2013
Effective melanoma inhibition by synthetic pentacyclic triterpenoid 2-(3-phenylprop-2-en-1-ylidene)-22β-hydroxy-3-oxoolean-12-en-28-oic acid: an in vitro and in vivo study.
The C-2 arylidene analog (compound 3) of pentacyclic triterpenoid Lantadene A (compound 1) was synthesized and evaluated by the… 
2007
2007
Synthesis, structural characterization, and in vitro antitumor activity of novel N-(6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)arylsulfonamides.
2006
2006
Efficacy of the Quinocarmycins KW 2152 and DX-521 against Human Melanoma Lines Growing in Culture and in Mice '
Quinocarmycin monocitrate (KW2152) and its analogue, DX-52.1, dean onstrated Specificityfor melanomas in the National Cancer… 
2006
2006
Cancer Therapy : Preclinical
Purpose: Advanced melanoma is a highly drug-refractory neoplasm representing a significant unmet medical need.We sought to… 
2004
2004
A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties.
2004
2004
Induction of growth inhibition and G1 arrest in human cancer cell lines by relatively low-toxic diamantane derivatives
We describe the discovery of a novel series of antitumor diamantane derivatives which induces G1 arrest in Colo 205 cells. Eight… 
2002
2002
An efficient, convenient synthesis of novel medium-sized 13H-dibenzo[d,h][1,3,7]oxadiazecine-8,14-dione macrolides as anticipated antineoplastic agents.
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