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UACC-257

A melanoma cell line established from a patient with cutaneous melanoma.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
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2015
2015
Pennogenyl saponins induce cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.
ETHNOPHARMACOLOGICAL RELEVANCE Pennogenyl saponins, the characterized components of Rhizoma Paridis, have been reported to have… (More)
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2013
2013
Characterization of NADPH oxidase 5 expression in human tumors and tumor cell lines with a novel mouse monoclonal antibody.
Reactive oxygen species generated by NADPH oxidase 5 (Nox5) have been implicated in physiological and pathophysiological… (More)
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2011
2011
Synthesis and in vitro screening of novel N-benzyl aplysinopsin analogs as potential anticancer agents.
A series of novel substituted (Z)-5-((1-benzyl-1H-indol-3-yl)methylene)imidazolidin-2,4-diones (3a-f) and (Z)-5-((1-benzyl-1H… (More)
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2009
2009
Synthesis and cytotoxic activity of alpha-santonin derivatives.
Ten alpha-santonin derivatives were synthesized in moderate to high yields. Four derivatives namely 10alpha-acetoxy-3-oxo-1… (More)
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2008
2008
Plitidepsin has a dual effect inhibiting cell cycle and inducing apoptosis via Rac1/c-Jun NH2-terminal kinase activation in human melanoma cells.
Melanoma is the most aggressive skin cancer and a serious health problem worldwide because of its increasing incidence and the… (More)
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2007
2007
Synthesis, structural characterization, and in vitro antitumor activity of novel N-(6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)arylsulfonamides.
A new series of N-(6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)arylsulfonamides 23-48 have been synthesized as potential… (More)
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2007
2007
Chemical composition and cytotoxic activity of the leaf essential oil of Eugenia zuchowskiae from Monteverde, Costa Rica
The leaf essential oil of Eugenia zuchowskiae from Monteverde, Costa Rica, has been obtained by hydrodistillation and analyzed by… (More)
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2005
2005
Synthesis and anticancer evaluation of certain 4-anilinofuro[2,3-b]quinoline and 4-anilinofuro[3,2-c]quinoline derivatives.
Certain linear 4-anilinofuro[2,3-b]quinoline and angular 4-anilinofuro[3,2-c]quinoline derivatives were synthesized and evaluated… (More)
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2001
2001
Development of C-20 modified betulinic acid derivatives as antitumor agents.
Chemical modifications were performed on C-20 position of betulinic acid for a structure-activity relationship study. The… (More)
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1995
1995
Efficacy of the quinocarmycins KW2152 and DX-52-1 against human melanoma lines growing in culture kand in mice.
Quinocarmycin monicitrate (KW2152) and its analogue, DX-52-1, demonstrated specificity for melanomas in the National Cancer… (More)
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