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U 78517F

Known as: U-78517F, U78517F 
National Institutes of Health

Papers overview

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Highly Cited
1996
Highly Cited
1996
Free radicals are implicated as causative agents in various forms of tissue destruction. Considerable circumstantial evidence… 
1995
1995
Selected 21-aminosteroids (U74500A, U74006F, and U74389G) and a 2-(aminomethyl)chromans (U78517F) were tested for their efficacy… 
1995
1995
Oxygen-based free radicals have been shown to play a major role in the acute destruction of neurons following cerebral ischemia… 
Highly Cited
1994
Highly Cited
1994
The antioxidant effects of SB 211475, a metabolite of carvedilol, a novel antihypertensive agent, were studied and compared with… 
1994
1994
Mechanisms of neuronal death after acute insults are unknown but may involve energy depletion and resultant glutamate toxicity… 
Highly Cited
1993
Highly Cited
1993
The generation of free radicals in the progression of kainic acid (KA)-mediated neuronal death has been implicated in both in… 
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1992
1992
1 Cytosolic calcium concentrations ([Ca2+]i were determined with fura‐2 on both resting (unstimulated) and A23187‐stimulated… 
Highly Cited
1991
Highly Cited
1991
U-78517F (2-[4-[2,6-di-(1-pyrrolidinyl)-4-pyridinyl)-1-piperazinyl] methyl]-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-6-ol… 
Highly Cited
1991
Highly Cited
1991
UNLABELLED Sepsis remains a leading cause of death in the surgical intensive care unit (SICU) patient following major surgery or… 
1990
1990
U78517F is a novel inhibitor of iron-catalyzed lipid peroxidation that combines the tetramethylchroman antioxidant ring portion…