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U 78517F

Known as: U-78517F, U78517F 
National Institutes of Health

Related topics

Related topics

9 relations
2-methyl aminochromanU 78517GU 83836E

Broader (5)

Anti-Asthmatic AgentsAntioxidantsChromansNeuroprotective Agents

Narrower (1)

PNU 83836E

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1996
Highly Cited
1996
Diisopropylphosphorofluoridate-induced muscle hyperactivity associated with enhanced lipid peroxidation in vivo.
1996
1996
An application of electron paramagnetic resonance to evaluate nitric oxide and its quenchers.
Electron paramagnetic resonance (EPR) spectrometry has been used for detection of free radicals, including nitric oxide (NO). The… 
Highly Cited
1996
Highly Cited
1996
Diisopropylphosphorofluoridate-induced cholinergic hyperactivity and lipid peroxidation.
In the present study, the association between acetylcholine (ACh)-induced muscle necrosis and the appearance of lipid… 
1995
1995
Two novel antioxidants, U74006F and U78517F, inhibit oxidant-stimulated calcium influx.
Highly Cited
1994
Highly Cited
1994
SB 211475, a metabolite of carvedilol, a novel antihypertensive agent, is a potent antioxidant.
Review
1994
Review
1994
In Vivo Generation of Hydroxyl Radicals and MPTP‐Induced Dopaminergic Toxicity in the Basal Ganglia
The in vivo generation of .OH free radicals in specific brain regions can be measured by intracerebral microdialysis perfusion of… 
1994
1994
Superoxide dismutase, catalase, and U78517F attenuate neuronal damage in gerbils with repeated brief ischemic insults
Repeated ischemic insults at one hour intervals result in more severe neuronal damage than a single similar duration insult. The… 
Highly Cited
1993
Highly Cited
1993
Use of a biophysical-kinetic model to understand the roles of protein binding and membrane partitioning on passive diffusion of highly lipophilic molecules across cellular barriers.
The novel antioxidants U-78517F and U-74006F, or lazaroids, are highly lipophilic organic molecules with poor brain uptake. To… 
Highly Cited
1991
Highly Cited
1991
Effect of oxygen-free radical scavengers on survival in sepsis.
UNLABELLED Sepsis remains a leading cause of death in the surgical intensive care unit (SICU) patient following major surgery or… 
1990
1990
Nonsteroidal lazaroid U78517F in models of focal and global ischemia.
U78517F is a novel inhibitor of iron-catalyzed lipid peroxidation that combines the tetramethylchroman antioxidant ring portion… 
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