U 78517F

Known as: U-78517F, U78517F 
 
National Institutes of Health

Papers overview

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1996
1996
Free radicals are implicated as causative agents in various forms of tissue destruction. Considerable circumstantial evidence… (More)
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1995
1995
Oxygen-based free radicals have been shown to play a major role in the acute destruction of neurons following cerebral ischemia… (More)
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1995
1995
Selected 21-aminosteroids (U74500A, U74006F, and U74389G) and a 2-(aminomethyl)chromans (U78517F) were tested for their efficacy… (More)
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1994
1994
Mechanisms of neuronal death after acute insults are unknown but may involve energy depletion and resultant glutamate toxicity… (More)
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1994
1994
The antioxidant effects of SB 211475, a metabolite of carvedilol, a novel antihypertensive agent, were studied and compared with… (More)
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1994
1994
Repeated ischemic insults at one hour intervals result in more severe neuronal damage than a single similar duration insult. The… (More)
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1993
1993
The generation of free radicals in the progression of kainic acid (KA)-mediated neuronal death has been implicated in both in… (More)
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1993
1993
Oxidative injury was initiated by addition of ferrous ammonium sulfate (FAS) to a suspension of whole rat brain homogenate in… (More)
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1991
1991
U-78517F (2-[4-[2,6-di-(1-pyrrolidinyl)-4-pyridinyl)-1-piperazinyl] methyl]-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-6-ol… (More)
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1990
1990
U78517F is a novel inhibitor of iron-catalyzed lipid peroxidation that combines the tetramethylchroman antioxidant ring portion… (More)
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