Tumor Hypoxia

Known as: Tumor Cell Hypoxias, Tumor Hypoxias, Hypoxia, Tumor Cell 
Hypoxic conditions in tumor cells due to the tumor outgrowing its blood supply. It is associated with increased METASTASIS and resistance to… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
As the result of genetic alterations and tumor hypoxia, many cancer cells avidly take up glucose and generate lactate through… (More)
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Highly Cited
2009
Highly Cited
2009
The current problems of malignant growth biology, in particular the molecular background of the specific microenvironment of… (More)
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Highly Cited
2008
Highly Cited
2008
Tumor hypoxia is linked to increased metastatic potential, but the molecular mechanisms coupling hypoxia to metastasis are poorly… (More)
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Review
2007
Review
2007
Hypoxia, a characteristic feature of locally advanced solid tumors, has emerged as a pivotal factor of the tumor (patho-)physiome… (More)
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Highly Cited
2007
Highly Cited
2007
Novel antiangiogenic strategies with complementary mechanisms are needed to maximize efficacy and minimize resistance to current… (More)
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Review
2004
Review
2004
Hypoxia is a characteristic feature of locally advanced solid tumors resulting from an imbalance between oxygen (O(2)) supply and… (More)
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Review
2001
Review
2001
Tissue hypoxia results from an inadequate supply of oxygen (O(2)) that compromises biologic functions. Evidence from experimental… (More)
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Highly Cited
2000
Highly Cited
2000
The transcriptional complex hypoxia-inducible factor-1 (HIF-1) has emerged as an important mediator of gene expression patterns… (More)
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Highly Cited
1997
Highly Cited
1997
PURPOSE Tumor hypoxia adversely affects short term clinical radiation response of head and neck cancer lymph node metastases and… (More)
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Highly Cited
1996
Highly Cited
1996
Experimental tumors contain a significant fraction of microregions that are chronically or transiently hypoxic. Experimental… (More)
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