Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Tropomodulin

Known as: Tropomodulin [Chemical/Ingredient] 
An actin capping protein that binds to the pointed-end of ACTIN. It functions in the presence of TROPOMYOSIN to inhibit microfilament elongation.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Regulation of actin filament dynamics underlies many cellular functions. Tropomodulin together with tropomyosin can cap the… Expand
Is this relevant?
2000
2000
PURPOSE To determine the role of the actin cytoskeleton regulatory proteins tropomyosin and tropomodulin (Tmod) in the… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The pointed end capping protein, tropomodulin, increases the critical concentration of barbed end capped actin,i.e. it lowers the… Expand
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Loss of myofibril organization is a common feature of chronic dilated and progressive cardiomyopathy. To study how the heart… Expand
  • figure 2
  • figure 1
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Tropomodulin is a tropomyosin-binding protein that terminates "pointed-end" actin filament polymerization. To test the hypothesis… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1995
Highly Cited
1995
CONTROL of actin filament length and dynamics is important for cell motility and architecture and is regulated in part by capping… Expand
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Tropomodulin is a pointed end capping protein for tropomyosin-coated actin filaments that is hypothesized to play a role in… Expand
  • figure I
  • figure 2
  • figure 3
  • figure 5
  • figure 7
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Many proteins have been shown to cap the fast growing (barbed) ends of actin filaments, but none have been shown to block… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1994
Highly Cited
1994
  • L. Sung, J. Lin
  • Biochemical and biophysical research…
  • 1994
  • Corpus ID: 37136543
Tropomodulin is a 40.6-kDa protein that binds to one end of the rod-like tropomyosin and inhibits its cooperativity and binding… Expand
Is this relevant?
Highly Cited
1990
Highly Cited
1990
  • V. Fowler
  • The Journal of cell biology
  • 1990
  • Corpus ID: 1044840
Human erythrocytes contain a Mr 43,000 tropomyosin-binding protein that is unrelated to actin and that has been proposed to play… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table II
Is this relevant?