Skip to search formSkip to main contentSkip to account menu

Tropomodulin

Known as: Tropomodulin [Chemical/Ingredient] 
An actin capping protein that binds to the pointed-end of ACTIN. It functions in the presence of TROPOMYOSIN to inhibit microfilament elongation.
National Institutes of Health

Related topics

Related topics

11 relations
In BloodProcess of secretionTMOD1 geneagonists

Narrower (2)

TMOD1 protein, humanTmod1 protein, rat

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Tubules of plant reoviruses exploit tropomodulin to regulate actin-based tubule motility in insect vector
Plant reoviruses are known to exploit virion-packaging tubules formed by virus-encoding non-structural proteins for viral spread… 
Highly Cited
2007
Highly Cited
2007
Tropomyosin modulates erythrocyte membrane stability.
The ternary complex of spectrin, actin, and 4.1R (human erythrocyte protein 4.1) defines the nodes of the erythrocyte membrane… 
2000
2000
The lens membrane skeleton contains structures preferentially enriched in spectrin-actin or tropomodulin-actin complexes.
The spectrin-based membrane skeleton plays an important role in determining the distributions and densities of receptors, ion… 
1999
1999
Tropomodulin isolated from rabbit skeletal muscle inhibits filament formation of actin in the presence of tropomyosin and troponin.
Tropomodulin is a tropomyosin-binding protein, originally isolated from human erythrocytes. Tropomodulin is currently regarded as… 
Review
1997
Review
1997
Capping actin filament growth: tropomodulin in muscle and nonmuscle cells.
Actin filament lengths are precisely regulated and very stable in the sarcomeres of striated muscle, in the erythrocyte membrane… 
1996
1996
Lens tropomodulin: developmental expression during differentiation.
Lens epithelial cells undergo a dramatic transformation during the process of differentiation into elongated fiber cells. The… 
1996
1996
Gene assignment, expression, and homology of human tropomodulin.
Tropomodulin is a newly characterized pointed end capping protein for actin filaments. It binds specifically to the N terminus of… 
1996
1996
Chicken skeletal muscle tropomodulin: novel localization and characterization
Abstract.Tropomodulin is a 40.6-kDa isoform-specific tropomyosin-binding protein which inhibits actin filament elongation from… 
Highly Cited
1994
Highly Cited
1994
Immunolocalization of tropomodulin, tropomyosin and actin in spread human erythrocyte skeletons.
The human erythrocyte membrane skeleton consists of a network of short actin filaments cross-linked into a hexagonal network by… 
1994
1994
Identification and characterization of tropomodulin and tropomyosin in the adult rat lens.
The lens fiber cells express all the major components of the erythrocyte membrane skeleton including spectrin, protein 4.1 and… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)