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Triethylenephosphoramide

Known as: Aziridine, 1,1',1''-phosphinylidynetris-, TEPA, Triethylenephosphoramide [Chemical/Ingredient] 
An insect chemosterilant and an antineoplastic agent.
National Institutes of Health

Related topics

Related topics

11 relations

Broader (1)

Antineoplastic Agents, Alkylating
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (3)

benzo-tepadiiodobenzotepafluorobenzotepa

Papers overview

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1986
1986
In the search for new anticancer drugs. 19. A predictive design of N,N:N',N':N'',N''-tri-1,2-ethanediylphosphorothioic triamide (TEPA) analogues.
The nitroxyl-labeled analogues of N,N:N',N':N",N"-tri-1,2-ethanediylphosphoric triamide (TEPA), N,N:N',N'-bis(1,2-ethanediyl)-N… 
1981
1981
Antitumor activities of seventeen alkylating agents against human mammary carcinoma (MS-1) in nude mice.
The antitumor activities of seventeen antitumor alkylating agents have been studied in the xenograft of human mammary carcinoma… 
1975
1975
Effects of in-vitro treatment of boar spermatozoa with TEPA on the fertilization and development of pig eggs.
Numerous studies have demonstrated the value of using heterospermic inseminations for comparing the fertilizing capacity of males… 
1974
1974
[Mutagenic effect of thio-TEPA in laboratory mice. II. Cytogenetic analysis of damage to bone marrow cells].
Highly Cited
1974
Highly Cited
1974
Induction of endoreduplication in cultured mammalian cells by some chemical mutagens.
Summary Chinese hamster cells treated with such chemical mutagens as 4-nitroquinoline 1-oxide, captan, acridine dyes, and Cytoxan… 
1966
1966
Effects of tepa on the reproductive organs and embryogeny of the German cockroach.
A rotary microtome was modified to inject precise amounts of tepa into German cockroaches, Blattella germanica (L.). Dosages of 0… 
1965
1965
TREATMENT OF BLADDER TUMORS BY INSTILLATION OF THIO-TEPA, ACTINOMYCIN D, OR 5-FLUOROURACIL.
1964
1964
TOXICITY OF METEPA TO RATS WITH NOTES ON TWO OTHER CHEMOSTERILANTS.
Although tepa, metepa, and apholate are only moderately toxic to rats by the oral route, the dermal toxicity of the first two is… 
1958
1958
The treatment of advanced malignant melanoma with triethylene thiophosphoramide (Thio-TEPA or TSPA).
1955
1955
The metabolism of 32P-labelled triethylenephosphoramide in relation to its anti-tumour activity.
Ethyleneimines such as triethylenephosphoramide (TEPA, I) and triethylenemelamine (TEM, II) (p. 325) exert remarkable inhibitory…