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Triethylenephosphoramide

Known as: Aziridine, 1,1',1''-phosphinylidynetris-, TEPA, Triethylenephosphoramide [Chemical/Ingredient] 
An insect chemosterilant and an antineoplastic agent.
National Institutes of Health

Related topics

Related topics

11 relations

Broader (1)

Antineoplastic Agents, Alkylating
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (3)

benzo-tepadiiodobenzotepafluorobenzotepa

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Chitosan based oligoamine polymers: synthesis, characterization, and gene delivery.
2009
2009
Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa.
AIMS Thiotepa is widely used in high-dose chemotherapy. Previous studies have shown relations between exposure and severe organ… 
Highly Cited
2004
Highly Cited
2004
Linear polyamine copper chelator tetraethylenepentamine augments long-term ex vivo expansion of cord blood-derived CD34+ cells and increases their engraftment potential in NOD/SCID mice.
Highly Cited
2000
Highly Cited
2000
Shrubsteppe Bird Response to Habitat and Landscape Variables in Eastern Washington, U.S.A.
Abstract: The landscape of the intermountain west has changed dramatically in the last 150 years, particularly in the state of… 
Highly Cited
1989
Highly Cited
1989
Phase I and pharmacokinetic evaluation of thiotepa in the cerebrospinal fluid and plasma of pediatric patients: evidence for dose-dependent plasma clearance of thiotepa.
A Phase I trial of thiotepa (TT) administered as an i.v. bolus was performed in 19 children with refractory malignancies. The… 
Highly Cited
1976
Highly Cited
1976
Intrathecal n, n′, n′‐triethylenethiophosphoramide [thio‐tepa (NSC 6396)] in the treatment of malignant meningeal disease. Phase I‐II study
N, N′, N″‐Triethylenethiophosphoramide [Thio‐TEPA (NSC 6396)] is the third drug to be evaluated for the treatment of meningeal… 
Highly Cited
1970
Highly Cited
1970
Intrapleural chemotherapy for effusion from metastatic breast carcinoma
Efficacy of thoracentesis with the instillation of nitrogen mustard or thio‐TEPA for malignant pleural effusions due to… 
Highly Cited
1962
Highly Cited
1962
Bladder carcinoma treated by direct instillation of thio-TEPA.
Highly Cited
1953
Highly Cited
1953
Clinical studies on triethylenephosphoramide and diethylenephosphoramide, compounds with nitrogen‐mustard‐like activity
RIETHYLENEMELAMINE (2,4,6-triethylenimi-T no-s-triazine 
Highly Cited
1953
Highly Cited
1953
Clinical studies on the carcinolytic action of triethylenephosphoramide
DEMONSTRATION of the carcinolytic prop-T erties of certain triazinescr 
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