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Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroyl-glutamic acid.
IT IS the purpose of this paper to record the results of clinical and hematologic studies on 5 children with acute leukemia treated by the intramuscular injection of a synthetic compound,Expand
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Chemical differentiation along metaphase chromosomes.
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Some observations on the effect of folic acid antagonists on acute leukemia and other forms of incurable cancer.
A general discussion is presented of the present status of folic acid antagonist therapy in acute leukemia in children and in other forms of incurable cancer. Conclusions reached in our initialExpand
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Lipogranulomatosis; a new lipo-glycoprotein storage disease.
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The question of stemlines in human acute leukemia. Comparison of cells isolated in vitro and in vivo from a patient with acute lymphoblastic leukemia.
Abstract Mononuclear, lymphoblastoid (CCRF-SB) cells isolated in suspension culture from the peripheral blood buffy coat of a child with acute lymphoblastic leukemia have been non-tumorigenic inExpand
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STUDIES ON PULMONARY EDEMA : I. THE CONSEQUENCES OF BILATERAL CERVICAL VAGOTOMY IN THE RABBIT.
1. Bilateral cervical vagotomy in rabbits soon leads to death, usually within 8 to 24 hours. 2. Gradually increasing dyspnea, crises with expulsion of frothy, serous or sanguineous fluid from theExpand
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NIEMANN‐PICK DISEASE: A REVIEW OF EIGHTEEN PATIENTS
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