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Treprostinil

Known as: treprostinil [Chemical/Ingredient], (1R,2R,3aS,9aS)-[[2,3,3a,4,9,9a-hexahydro-2-hydroxy- 1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl] oxy]acetic acid, Treprostinilo 
National Institutes of Health

Related topics

Related topics

19 relations
12 HR Treprostinil 1 MG Extended Release Oral Tablet [Orenitram]12 HR Treprostinil 2.5 MG Extended Release Oral TabletDecreased Blood Pressure [PE]Hypersensitivity

Broader (2)

Antihypertensive AgentsEpoprostenol

Narrower (5)

RemodulinTyvasoUT-15Uniprost

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
The mechanistic basis of prostacyclin and its stable analogues in pulmonary arterial hypertension: Role of membrane versus nuclear receptors.
Highly Cited
2010
Highly Cited
2010
Long-term outcomes in children with pulmonary arterial hypertension treated with bosentan in real-world clinical settings.
Highly Cited
2007
Highly Cited
2007
Treprostinil for severe inoperable chronic thromboembolic pulmonary hypertension
Background: Chronic thromboembolic pulmonary hypertension (CTEPH) results from non‐resolving pulmonary thromboemboli that are… 
Highly Cited
2007
Highly Cited
2007
IP receptor-dependent activation of PPARγ by stable prostacyclin analogues
Review
2007
Review
2007
Evidence-based pharmacologic management of pulmonary arterial hypertension.
Highly Cited
2006
Highly Cited
2006
Selective serotonin reuptake inhibitor use and outcomes in pulmonary arterial hypertension.
Highly Cited
2006
Highly Cited
2006
Comparison and validation of three measures of quality of life in patients with pulmonary hypertension
Background: Pulmonary hypertension, when advanced, markedly limits exercise capacity, activities of daily living and quality of… 
Highly Cited
2005
Highly Cited
2005
Transition from intravenous epoprostenol to intravenous treprostinil in pulmonary hypertension.
RATIONALE Intravenous epoprostenol improves exercise capacity and survival in patients with pulmonary arterial hypertension. The… 
Highly Cited
2005
Highly Cited
2005
Acute and chronic effects of sildenafil in patients with pulmonary arterial hypertension.
Review
2004
Review
2004
Prostacyclin and its analogues in the treatment of pulmonary hypertension.
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