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Tremorine

Known as: Pyrrolidine, 1,1'-(2-butyne-1,4-diyl)bis-, Tremorine [Chemical/Ingredient] 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Tremorine-induced tremors model is used to evaluate antiparkinsonian drugs because rest tremor is a sign that distinguishes… Expand
1969
1969
1 The relationship between tremor and change in brain acetylcholine concentration after the injection of tremorine or… Expand
Highly Cited
1968
Highly Cited
1968
1. Strips of longitudinal muscle can be obtained from guinea‐pig ileum either retaining or free from Auerbach's plexus. 
1968
1968
Abstract In rats drugs may delay or block the syndrome induced by tremorine (TMN) either by decelerating its bioactivation to… Expand
Review
1968
Review
1968
DRUGS and other compounds capable of causing sustained trembling are rare; in a survey of ten thousand compounds Everett et al… Expand
1964
1964
Abstract Sprague-Dawley rats averaging 360 g and between 6 and 10 months old were housed under standardized conditions. Groups of… Expand
Highly Cited
1963
Highly Cited
1963
Abstract Tremorine increases the content of brain acetylcholine (AcCh) by as much as 40% by an action is not due to an inhibition… Expand
Highly Cited
1962
Highly Cited
1962
The peripheral pharmacology of oxotremorine [1(2-oxopyrrolidino)-4-pyrrolidino-butyne-2], a metabolite of tremorine, has been… Expand
Highly Cited
1962
Highly Cited
1962
Highly Cited
1958
Highly Cited
1958
  • G. Chen
  • The Journal of pharmacology and experimental…
  • 1958
  • Corpus ID: 2479163
Tremorine has been shown to produce analgesia in mice by Haffner9s method. The Tremorine-induced analgesia may be antagonized by… Expand