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Translation Initiation

Known as: biopolymerisation, biopolymerization, translational initiation 
Translation Initiation consists of cellular and enzymatic reactions that instigate the process by which polypeptides are synthesized on ribosomes… 
National Institutes of Health

Related topics

Related topics

48 relations
DENR geneDENR protein, humanDENR wt AlleleEIF1 gene

Broader (2)

Protein Biosynthesisprotein synthesis initiation

Narrower (4)

formation of translation preinitiation complexmethionyl-tRNA formyltransferase activitymitochondrial translational initiationtranslation initiation factor activity

Papers overview

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Highly Cited
2010
Highly Cited
2010
An Evolutionarily Conserved Mechanism for Controlling the Efficiency of Protein Translation
Highly Cited
2007
Highly Cited
2007
Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity.
Expression of eukaryotic translation initiation factor 4E (eIF4E) is commonly elevated in human and experimental cancers… 
Review
2006
Review
2006
The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A).
The eukaryotic translation initiation factor 5A (eIF5A) is the only cellular protein that contains the unique polyamine-derived… 
Highly Cited
2003
Highly Cited
2003
Growth Arrest and DNA Damage-Inducible Protein GADD34 Targets Protein Phosphatase 1α to the Endoplasmic Reticulum and Promotes Dephosphorylation of the α Subunit of Eukaryotic Translation Initiation…
ABSTRACT The growth arrest and DNA damage-inducible protein, GADD34, associates with protein phosphatase 1 (PP1) and promotes in… 
Highly Cited
2001
Highly Cited
2001
Subunits of the translation initiation factor eIF2B are mutant in leukoencephalopathy with vanishing white matter
Leukoencephalopathy with vanishing white matter (VWM) is an inherited brain disease that occurs mainly in children. The course is… 
Review
1998
Review
1998
Control of translation initiation in animals.
Regulation of translation initiation is a central control point in animal cells. We review our current understanding of the… 
Highly Cited
1998
Highly Cited
1998
Phosphorylation of Eukaryotic Translation Initiation Factor 2 Mediates Apoptosis in Response to Activation of the Double-stranded RNA-dependent Protein Kinase*
The interferon-inducible, double-stranded (ds) RNA-dependent serine/threonine protein kinase (PKR) plays a role in viral… 
Highly Cited
1998
Highly Cited
1998
Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons
The scanning model of translation initiation is a coherent description of how eukaryotic ribosomes reach the initiation codon… 
Highly Cited
1991
Highly Cited
1991
Internal initiation of translation mediated by the 5′ leader of a cellular mRNA
A RIBOSOME-SCANNING model has been proposed to explain the initiation of eukaryotic messenger RNAs1 in which binding of the 43S… 
Highly Cited
1971
Highly Cited
1971
Research Communication
The crystal structures of the full-length human eukaryotic initiation factor (eIF) 4E complexed with two mRNA cap analogues [7… 
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