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Transforming Acidic Coiled-Coil Containing Protein 3

Known as: ERIC1, TACC3, Transforming Acidic Coiled-Coil-Containing Protein 3 
Transforming acidic coiled-coil-containing protein 3 (838 aa, ~90 kDa) is encoded by the human TACC3 gene. This protein may play a role in… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
CHC binds specifically to aurora A–phosphorylated TACC3, recruiting it to the spindle during mitosis. 
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Highly Cited
2010
Highly Cited
2010
The glioblastoma genome displays remarkable chromosomal aberrations, which harbor critical glioblastoma-specific genes… Expand
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2010
2010
Studies of the role of tuberous sclerosis complex (TSC) proteins (TSC1/TSC2) in pathology have focused mainly on their capacity… Expand
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Highly Cited
2008
Highly Cited
2008
Formation of female gametes requires acentriolar spindle assembly during meiosis. Mitotic spindles organize from centrosomes and… Expand
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Highly Cited
2007
Highly Cited
2007
Aurora A is a serine/threonine protein kinase essential for normal mitotic progression. Aberrant increased expression of Aurora A… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT NDEL1 is a binding partner of LIS1 that participates in the regulation of cytoplasmic dynein function and microtubule… Expand
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Highly Cited
2006
Highly Cited
2006
Transforming acidic coiled-coil containing protein 3 (TACC3) is known to be involved in the control of normal cell growth and… Expand
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Highly Cited
2005
Highly Cited
2005
Centrosomes act as sites of microtubule growth, but little is known about how the number and stability of microtubules emanating… Expand
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Highly Cited
2003
Highly Cited
2003
The three human TACC (transforming acidic coiled-coil) genes encode a family of proteins with poorly defined functions that are… Expand
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Highly Cited
2002
Highly Cited
2002
TACC3 is a centrosomal/mitotic spindle‐associated protein that is highly expressed in a cell cycle‐dependent manner in… Expand
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