Transforming Acidic Coiled-Coil Containing Protein 3

Known as: ERIC1, TACC3, Transforming Acidic Coiled-Coil-Containing Protein 3 
Transforming acidic coiled-coil-containing protein 3 (838 aa, ~90 kDa) is encoded by the human TACC3 gene. This protein may play a role in… (More)
National Institutes of Health

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Cell Cycle ControlGenes, RegulatorGenes, cdcTACC3 gene
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Papers overview

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2017
2017
Overexpression of Transforming Acidic Coiled Coil‑Containing Protein 3 Reflects Malignant Characteristics and Poor Prognosis of Glioma
Gliomas are malignant primary brain tumors with poor prognosis. Recently, research was indicative of a tight connection between… (More)
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2017
2017
Clinicopathological and prognostic value of transforming acidic coiled-coil-containing protein 3 (TACC3) expression in soft tissue sarcomas
Transforming acidic coiled-coil-containing protein 3 (TACC3), a microtubule regulator, is associated with various cancers… (More)
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2016
2016
The clinical significance of transforming acidic coiled-coil protein 3 expression in non-small cell lung cancer.
The relationship between TACC3, a member of the transforming acidic coiled-coil proteins (TACCs) family, and lung carcinoma… (More)
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2015
2015
Transforming acidic coiled-coil-containing protein 3 (TACC3) overexpression in hepatocellular carcinomas is associated with “stemness” and epithelial-mesenchymal transition-related marker expression…
There is accumulating evidence that hepatocellular carcinomas (HCCs) expressing “stemness”-related markers, e.g., keratin 19 (K19… (More)
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2007
2007
Transforming acidic coiled-coil 3 and Aurora-A interact in human thyrocytes and their expression is deregulated in thyroid cancer tissues
Aurora-A kinase has recently been shown to be deregulated in thyroid cancer cells and tissues. Among the Aurora-A substrates… (More)
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2007
2007
The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival.
Cancer-associated centrosomal transforming acidic coiled coil (TACC) proteins are involved in mitotic spindle function. By… (More)
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2006
2006
Expression of transforming acidic coiled-coil containing protein 3 is a novel independent prognostic marker in non-small cell lung cancer.
Transforming acidic coiled-coil containing protein 3 (TACC3) is known to be involved in the control of normal cell growth and… (More)
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2004
2004
Structure-function evolution of the Transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organisms
Examination of ancient gene families can provide an insight into how the evolution of gene structure can relate to function… (More)
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2004
2004
Transforming acidic coiled-coil protein 3 (TACC3) controls friend of GATA-1 (FOG-1) subcellular localization and regulates the association between GATA-1 and FOG-1 during hematopoiesis.
Physical association between the transcription factor GATA-1 and the cofactor, Friend of GATA-1 (FOG-1), is essential for the… (More)
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2002
2002
The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis.
TACC3 is a centrosomal/mitotic spindle-associated protein that is highly expressed in a cell cycle-dependent manner in… (More)
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