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Transcription Factor TFIIIA

Known as: 5S Gene-Specific Transcription Factor, 5S Gene Specific Transcription Factor, TFIIIA 
One of several general transcription factors that are specific for RNA POLYMERASE III. It is a zinc finger (ZINC FINGERS) protein and is required for… Expand
National Institutes of Health

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11 relations
GTF3A geneIn BloodProcess of secretionRNA, Ribosomal, 5S
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OPTN protein, human

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Highly Cited
1997
Highly Cited
1997
Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores.
An essential cellular factor for nuclear mRNA export called Mex67p which has homologous proteins in human and Caenorhabditis… Expand
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Highly Cited
1993
Highly Cited
1993
A positive role for histone acetylation in transcription factor access to nucleosomal DNA
Acetylation of the N-terminal tails of the core histones directly facilitates the recognition by TFIIIA of the 5S RNA gene within… Expand
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Highly Cited
1993
Highly Cited
1993
Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers.
Zinc finger proteins, of the type first discovered in transcription factor IIIA (TFIIIA), are one of the largest and most… Expand
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Highly Cited
1992
Highly Cited
1992
Mutant conformation of p53. Precise epitope mapping using a filamentous phage epitope library.
Many naturally occurring point mutations in the p53 gene lead to a proportion of the encoded protein molecules adopting a… Expand
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Highly Cited
1990
Highly Cited
1990
S. cerevisiae TFIIIB is the transcription initiation factor proper of RNA polymerase III, while TFIIIA and TFIIIC are assembly factors
The S. cerevisiae RNA polymerase III (pol III) transcription factor TFIIIB binds to DNA upstream of the transcription start site… Expand
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Highly Cited
1987
Highly Cited
1987
A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor.
Nerve growth factor (NGF) is a trophic agent that promotes the outgrowth of nerve fibers from sympathetic and sensory ganglia… Expand
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Highly Cited
1987
Highly Cited
1987
The LINE-1 DNA sequences in four mammalian orders predict proteins that conserve homologies to retrovirus proteins.
Recent work suggests that one or more members of the highly repeated LINE-1 (L1) DNA family found in all mammals may encode one… Expand
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Highly Cited
1986
Highly Cited
1986
Structural homology of the product of the Drosophila Krüppel gene with Xenopus transcription factor IIIA
Segmentation of the Drosophila embryo is established at around the blastoderm stage1–3 and requires both maternal information in… Expand
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Highly Cited
1985
Highly Cited
1985
The primary structure of transcription factor TFIIIA has 12 consecutive repeats.
Analysis of the amino acid sequence of transcription factor TFIIIA from Xenopus laevis reveals the presence of 12 repeating… Expand
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Highly Cited
1984
Highly Cited
1984
Xenopus 5S gene transcription factor, TFIIIA: Characterization of a cDNA clone and measurement of RNA levels throughout development
Initiation of 5S RNA gene transcription in Xenopus oocytes requires a 38,500 dalton polypeptide, TFIIIA. The levels of both 5S… Expand
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