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Toxicogenetics

The study of existing genetic knowledge, and the generation of new genetic data, to understand and thus avoid DRUG TOXICITY and adverse effects from… 
National Institutes of Health

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Educational aspectsGenetic Toxicologylegislation & jurisprudencestandards characteristics

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Toxicogenomics

Papers overview

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Review
2013
Review
2013
Genetic risk prediction: individualized variability in susceptibility to toxicants.
Genetic risk prediction uses genetic data to individualize prediction of outcome or effect from a known harmful toxicant. Several… 
Review
2011
Review
2011
The toxicogenetics of antiretroviral therapy: the evil inside.
The most important factor limiting the success of an antiretroviral therapy regimes is toxicity. Toxicity can depend on a number… 
2008
2008
Low frequency of the glutathione-S-transferase T1-null genotype in patients with primary myelodysplastic syndrome and 5q deletion
Low frequency of the glutathione- S -transferase T1-null genotype in patients with primary myelodysplastic syndrome and 5q… 
Review
2008
Review
2008
[Toxicogenetics of antiretroviral treatment (II): neurotoxicity, hepatotoxicity, lactic acidosis, kidney damage, and other adverse effects of antiretroviral drugs].
Several pharmacogenetics studies have analyzed the influence of specific genetic polymorphisms on the toxicity of antiretroviral… 
Review
2007
Review
2007
Toxicogenetics of Antiretroviral Therapy: Genetic Factors that Contribute to Metabolic Complications
Metabolic complications of antiretroviral therapy (ART) have emerged as a major concern for long-term, successful management of… 
Review
2004
Review
2004
Genetic Variation and Exposure Related Risk Estimation: Will Toxicology Enter a New Era? DNA Repair and Cancer as a Paradigm
With the vast technological and informational resources increasingly available from investments in “genomics,” toxicology and… 
2003
2003
Genomics and Toxic Substances: Part II - Toxicogenetics
The sequencing of the human genome revealed that the variation in the genetic material between any two individuals averages… 
2002
2002
From pharmacogenetics and ecogenetics to pharmacogenomics.
The origin and development of pharmacogenetics are traced with emphasis on early hints by Garrod, Haldane, and later by RJ… 
Review
2001
Review
2001
Toxicogenetics in drug development.
1986
1986
Possible ethnic difference in toluene metabolism: a comparative study among Chinese, Turkish and Japanese solvent workers.
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