Torsades de Pointes

Known as: de Pointes, Torsades, Pointes, Torsades de, des pointe torsade 
A malignant form of polymorphic ventricular tachycardia that is characterized by HEART RATE between 200 and 250 beats per minute, and QRS complexes… (More)
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Torsades de pointes (TdP)-an uncommon but life-threatening polymorphic ventricular tachycardia-is almost always drug induced. The… (More)
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Review
2008
Review
2008
Drug-induced torsades de pointes (TdP) arrhythmia is a major safety concern in the process of drug design and development. The… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Identification of patients at risk for drug-induced torsades de pointes arrhythmia (TdP) is difficult. Increased… (More)
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Review
2003
Review
2003
OBJECTIVE To attempt to determine the relative value of preclinical cardiac electrophysiology data (in vitro and in vivo) for… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND DNA variants appearing to predispose to drug-associated "acquired" long-QT syndrome (aLQTS) have been reported in… (More)
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Review
1999
Review
1999
In the long QT syndromes (LQTS), malfunction of ion channels impairs ventricular repolarisation and triggers a characteristic… (More)
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Highly Cited
1998
Highly Cited
1998
In this retrospective case-control study, 8 of 223 consecutive patients (3.6%) treated with intravenous haloperidol developed… (More)
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1998
1998
Two cases of torsades de pointes associated with cisapride are presented, both in association with concomitant drug therapy that… (More)
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1990
1990
A patient had torsades de pointes ventricular tachycardia related to psychotherapy with haloperidol in conventional doses. The QT… (More)
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Highly Cited
1972
Highly Cited
1972
Repeated electrical stimulation of certain brain areas in the rat can decrease thresholds for epileptiform after-discharge (AD… (More)
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