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Torsades de Pointes

Known as: de Pointes, Torsades, Pointes, Torsades de, des pointe torsade 
A malignant form of polymorphic ventricular tachycardia that is characterized by HEART RATE between 200 and 250 beats per minute, and QRS complexes… 
National Institutes of Health

Related topics

Related topics

27 relations

Broader (3)

Autonomic nervous system disordersTachycardiaTachycardia, Ventricular
CDISC SDTM ECG Finding TerminologyClinical Data Interchange Standards Consortium TerminologyIn BloodIsoproterenol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Combined pharmacological block of IKr and IKs increases short‐term QT interval variability and provokes torsades de pointes
Assessing the proarrhythmic potential of compounds during drug development is essential. However, reliable prediction of drug… 
Highly Cited
2004
Highly Cited
2004
NAD+ Modulates p53 DNA Binding Specificity and Function
ABSTRACT DNA damage induces p53 DNA binding activity, which affects tumorigenesis, tumor responses to therapies, and the… 
Highly Cited
1997
Highly Cited
1997
Electrophysiologic Features of Torsades de Pointes:
Torsades de Pointes in the Isolated Rabbit Heart. Introduction: The exact electrophysiologic mechanism of torsades de pointes… 
Review
1997
Review
1997
Torsade de pointes and low-dose oral haloperidol.
Haloperidol, used to treat patients with psychoses, is considered minimally cardiotoxic. Several cases of torsade de pointes have… 
Highly Cited
1994
Highly Cited
1994
Purification to homogeneity of UDP-glucose:glycoprotein glucosyltransferase from Schizosaccharomyces pombe and apparent absence of the enzyme fro Saccharomyces cerevisiae.
Review
1988
Review
1988
Safety Overview: Toxicity, Adverse Effects, and Drug Interactions
1986
1986
Amiodarone-induced torsades de pointes.
Five cases of amiodarone-induced syncope due to torsades de pointes or ventricular fibrillation are described. Amiodarone was… 
Highly Cited
1983
Highly Cited
1983
A Mechanism of Torsades de Pointes in a Canine Model
A dog model of torsades de pointes (TdP) was developed. Twenty 18–30-kg dogs had cardiopulmonary bypass instituted to maintain… 
Highly Cited
1972
Highly Cited
1972
Human phosphoribosylpyrophosphate synthetase. Kinetic mechanism and end product inhibition.
Abstract Human PP-ribose-P synthetase, partially purified from erythrocytes, was found to have Michaelis constants for ribose-5-P… 
Highly Cited
1965
Highly Cited
1965
A biochemical and autoradiographic study of the in vivo utilization of tritiated thymidine in regenerating rat liver.
The utilization of tritiated thymidine as a measure of DNA[2][1] synthesis in 21-hr regenerating rat liver under specific… 
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