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Topical Piperidine Nitroxide MTS-01

Known as: TEMPOL, MTS-01, 1-Piperidinyloxy, 4-Hydroxy-2,2,6,6-tetramethyl- 
A topical gel containing a cell permeable hydrophilic piperidine nitroxide with potential radioprotective and antioxidant activity. As a stable, free… 
National Institutes of Health

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tempol

Papers overview

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2017
2017
Reactive Oxygen Species within the Spinal Cord Impairs Arterial Baroreflex Control of Renal Sympathetic Nerve Activity
Clinical and experimental studies have shown that sustained increase in renal sympathetic nerve activity (rSNA) contributes to… 
2014
2014
Comparative Effectiveness of Defatted Hypotensive Crude Extract, Ethyl Acetate and Butanolic Fractions of Cassytha filiformis L. on Different Models of Hypertensive Rats
The hypotensive effectiveness of defatted crude ethanolic extract, ethyl acetate and butanolic fractions of Cassytha filiformis L… 
2012
2012
Chronic treatment with tempol does not significantly ameliorate renal tissue hypoxia or disease progression in a rodent model of polycystic kidney disease
In the present study, we tested whether polycystic kidney disease (PKD) is associated with renal tissue hypoxia and oxidative… 
2009
2009
A new PIXel in the puzzle: how increased vascular pressure induces oxidative stress.
Hypertension is a clinical situation associated with endothelial dysfunction and increased vascular reactive oxygen species (ROS… 
2008
2008
Reactive Oxygen Species Mediate p 53 Activation and Apoptosis Induced by Sodium Nitroprusside in SH-SY 5 Y Cells
Sodium nitroprusside (SNP) is a water-soluble iron nitrosyl complex clinically used as a powerful vasodilator for treatment of… 
2006
2006
Cisplatin-induced renal injury in LLC-PK 1 cells
Nephrotoxicity is one of the important adverse effects induced by cisplatin (CDDP), a potent anticancer drug. CDDP causes a… 
2005
2005
Role of NADPH Oxidase in Hypertension and Diabetic Nephropathy
Oxidative stress plays an important role in the development of renal damage in diabetes and hypertension. The major source of… 
2003
2003
, Jr Leads to Hypertension 2 O 2 Increased Renal Medullary
We have recently reported that exaggerated oxidative stress in the renal medulla due to superoxide dismutase inhibition resulted… 
2001
2001
Oxidative stress enhances the production and actions of adenosine in the kidney
[PDF] [Full Text] [Abstract] , January 1, 2004; 43 (1): 57-63. Hypertension M. W. Brands, T. D. Bell and B. Gibson of… 
1975
1975
Permeation of a spin-label phosphate into the human erythrocyte.
The reduction of spin-labels by human erythrocytes can be used to follow their penetration into these cells. The neutral spin…