Topical Piperidine Nitroxide MTS-01

Known as: TEMPOL, MTS-01, 1-Piperidinyloxy, 4-Hydroxy-2,2,6,6-tetramethyl- 
A topical gel containing a cell permeable hydrophilic piperidine nitroxide with potential radioprotective and antioxidant activity. As a stable, free… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
RATIONALE Superoxide (O2(-) ) has been implicated in the pathogenesis of many human diseases including hypertension; however… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
Highly Cited
2010
Highly Cited
2010
AIMS Oxidative stress is known to be a major mechanism of endothelial dysfunction, which plays a key role in the development of… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Accumulating evidence suggests that mineralocorticoid receptor blockade effectively reduces proteinuria in hypertensive patients… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
BACKGROUND Reactive oxygen species (ROS) have been implicated in the development of cardiovascular pathologies. NAD(P)H oxidases… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Studies were performed to test the hypothesis that reactive oxygen species (ROS) and mitogen-activated protein kinase (MAPK… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
BACKGROUND Oxidative stress increases in hypertension. The aim of this study was to determine whether reactive oxygen species… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Although arsenic is a well-established human carcinogen, the mechanisms by which it induces cancer remain poorly understood. We… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • table 1
Is this relevant?
Highly Cited
1999
Highly Cited
1999
8-Iso prostaglandin F2alpha (8-ISO) is formed nonenzymatically from the attack of superoxide radical on arachidonic acid… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Superoxide radical (O2-) is increased in the vessel wall of spontaneously hypertensive rats (SHR) where its blockade potentiates… (More)
  • figure 1
  • figure 4
  • figure 2
  • figure 3
  • figure 5
Is this relevant?
Review
1994
Review
1994
This article provides a comprehensive analysis of the redox reaction between glutathione/glutathione disulfide and ascorbic acid… (More)
Is this relevant?