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Toll-Like Receptor 5

Known as: Receptor, TLR5, Toll-Like Receptor 5 [Chemical/Ingredient], TLR5 Receptor 
A pattern recognition receptor that binds FLAGELLIN. It mediates cellular responses to certain bacterial pathogens.
National Institutes of Health

Related topics

Related topics

10 relations
In BloodTLR5 geneTLR5 wt Alleleagonists

Narrower (2)

TLR5 protein, humantehao protein, Drosophila

Broader (1)

Toll-like receptors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Genetic Variations in Pattern Recognition Receptor Loci Are Associated with Anti-TNF Response in Patients with Rheumatoid Arthritis
Objectives To determine whether genetic variation within genes related to the Toll-like receptor, inflammasome and interferon… 
2013
2013
A Non-Synonymous Coding Variant (L616F) in the TLR5 Gene Is Potentially Associated with Crohn's Disease and Influences Responses to Bacterial Flagellin
Background and Objectives Although numerous studies have implicated TLR5, or its ligands, bacterial flagellins, in the… 
Highly Cited
2010
Highly Cited
2010
TRIF Mediates Toll-like Receptor 5-induced Signaling in Intestinal Epithelial Cells*
Toll-like receptors (TLRs) associate with adaptor molecules (MyD88, Mal/TIRAP, TRAM, and TRIF) to mediate signaling of host… 
2010
2010
TRIF Modulates TLR5-dependent Responses by Inducing Proteolytic Degradation of TLR5*
Proteolytic modification of pattern recognition receptors and their signaling adaptor molecules has recently emerged as an… 
2009
2009
Myeloid RelA regulates pulmonary host defense networks
The pulmonary innate immune system in the respiratory tract eliminates inhaled pathogens. Several cell types contribute to host… 
Highly Cited
2008
Highly Cited
2008
Presymptomatic differences in Toll-like receptor function in infants who have allergy.
Highly Cited
2008
Highly Cited
2008
Novel NOD2 haplotype strengthens the association between TLR4 Asp299gly and Crohn's disease in an Australian population
Background: The first major Crohn's disease (CD) susceptibility gene, NOD2, implicates the innate intestinal immune system and… 
Highly Cited
2007
Highly Cited
2007
Association study of Toll-like receptor 5 (TLR5) and Toll-like receptor 9 (TLR9) polymorphisms in systemic lupus erythematosus.
OBJECTIVE Toll-like receptors (TLR) play an important role in both adaptive and innate immunity. Variations in TLR genes have… 
2007
2007
Expression profiles and function of Toll-like receptors in human corneal epithelia.
BACKGROUND Toll-like receptors play an important role in the human immune system. This study was conducted to investigate the… 
2006
2006
Response of toll-like receptors, lysozyme, and IGF-I in back-cross hybrid (F1 male (blue x channel) x female channel) catfish challenged with virulent Edwardsiella ictaluri.
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