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Toll-Like Receptor 5

Known as: Receptor, TLR5, Toll-Like Receptor 5 [Chemical/Ingredient], TLR5 Receptor 
A pattern recognition receptor that binds FLAGELLIN. It mediates cellular responses to certain bacterial pathogens.
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Toll-like receptors (TLRs) recognize distinct microbial components and induce innate immune responses. TLR5 is triggered by… Expand
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE The transmembrane receptor family of Toll-like receptors (TLRs) may play a role in initiating early inflammatory and… Expand
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Highly Cited
2006
Highly Cited
2006
Toll-like receptors (TLRs) are key components of the immune system that detect microbial infection and trigger antimicrobial host… Expand
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Highly Cited
2005
Highly Cited
2005
Toll-like receptor 5 (TLR5) recognizes an evolutionarily conserved site on bacterial flagellin that is required for flagellar… Expand
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Highly Cited
2004
Highly Cited
2004
The distribution of specific toll-like receptors and components of the signaling pathways activated by Pseudomonas aeruginosa… Expand
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Review
2002
Review
2002
The mammalian Toll-like receptors (TLRs) are expressed on macrophages and dendritic cells, which are primarily involved in innate… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND & AIMS Bacterial wall products play an important role in the activation of immune and nonimmune cells of the… Expand
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Highly Cited
2001
Highly Cited
2001
Toll-like receptors (TLRs) mediate innate immune responses to microbes. TLR2, TLR5, TLR6, and TLR9 have been implicated in… Expand
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Highly Cited
2000
Highly Cited
2000
Initiation and perpetuation of the inflammatory intestinal responses in inflammatory bowel disease (IBD) may result from an… Expand
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Highly Cited
2000
Highly Cited
2000
Members of the Toll-like receptor (TLR) family probably play a fundamental role in pathogen recognition and activation of innate… Expand
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