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Tobramycin

Known as: Nebramycin Factor 6, Nebramycin-Faktor 6, Nebramycin factir 6 
An aminoglycoside antibiotic derived from Streptomyces tenebrarius with bacteriostatic activity. Following active transport into the cell, tobramycin… 
National Institutes of Health

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37 relations

Narrower (7)

6''-O-carbamoyltobramycin6'-N-acetyltobramycinBrulamycinNebcin
AminoglycosidesBACILLUS SUBTLIS MICROBIOLOGY ASSAY, TOBRAMYCINBacterial InfectionsDecreased Protein Synthesis [PE]

Broader (1)

Anti-Bacterial Agents

Papers overview

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Highly Cited
2011
Highly Cited
2011
In vitro activity of CXA-101 plus tazobactam (CXA-201) against CTX-M-14- and CTX-M-15-producing Escherichia coli and Klebsiella pneumoniae.
Highly Cited
2009
Highly Cited
2009
Particle characterization of poorly water-soluble drugs using a spray freeze drying technique.
A spray freeze drying (SFD) method was developed to prepare the composite particles of poorly water-soluble drug. The aqueous… 
Highly Cited
2006
Highly Cited
2006
Antimicrobial resistance in food and clinical Aeromonas isolates.
Highly Cited
2004
Highly Cited
2004
Effect of once-daily dosing vs. multiple daily dosing of tobramycin on enzyme markers of nephrotoxicity
Objective:To determine the incidence of nephrotoxicity of once-daily dosing (ODD) and multiple daily dosing (MDD) regimens of… 
Highly Cited
1985
Highly Cited
1985
Action of phospholipase A2 on bilayers. Effect of inhibitors.
Highly Cited
1984
Highly Cited
1984
Protective activity of an intravenous immune globulin (human) enriched in antibody against lipopolysaccharide antigens of Pseudomonas aeruginosa.
Highly Cited
1983
Highly Cited
1983
Controlled comparison of gentamicin and tobramycin nephrotoxicity.
317 patients with suspected or documented infections other than cystitis were randomly assigned to receive gentamicin or… 
Highly Cited
1978
Highly Cited
1978
Comparative Nephrotoxicity of Gentamicin and Tobramycin in Rats
A rat model was utilized to compare the nephrotoxic potential of gentamicin and tobramycin. Gentamicin, 40 mg/kg per day… 
Highly Cited
1975
Highly Cited
1975
Empiric Therapy for Cancer Patients: Comparative Study of Ticarcillin-Tobramycin, Ticarcillin-Cephalothin, and Cephalothin-Tobramycin
Three combinations of antibiotics (cephalothin-tobramycin, cephalothin-ticarcillin, and ticarcillin-tobramycin) were administered… 
Highly Cited
1974
Highly Cited
1974
Therapeutic trials with tobramycin
Tobramycin, a new aminoglycoside, was utilized in the treatment of 82 infectious episodes in 73 cancer patients. Forty-four… 
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