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Tn Antigen-MUC1-32mer Antibody

Known as: Anti-Tn Antigen-MUC1-32mer Antibody, Anti-Tn-MUC1-32mer Antibody, Tn-MUC1-32mer Antibody 
Any immunoglobulin that recognizes a conjugate immunogen comprised of the carbohydrate antigen Tn and 32 amino acids of mucin-1 protein.
National Institutes of Health

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2 relations
Immune System Processesantigen binding

Papers overview

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Highly Cited
2013
Highly Cited
2013
MUC1 vaccine for individuals with advanced adenoma of the colon: a cancer immunoprevention feasibility study.
Cancer vaccines based on human tumor-associated antigens (TAA) have been tested in patients with advanced or recurrent cancer, in… Expand
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2011
2011
Natural and Induced Humoral Responses to MUC1
MUC1 is a membrane-tethered mucin expressed on the ductal cell surface of glandular epithelial cells. Loss of polarization… Expand
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2011
2011
Lectin Domains of Polypeptide GalNAc Transferases Exhibit Glycopeptide Binding Specificity*
UDP-GalNAc:polypeptide α-N-acetylgalactosaminyltransferases (GalNAc-Ts) constitute a family of up to 20 transferases that… Expand
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Highly Cited
2010
Highly Cited
2010
Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis
IntroductionDetection of serum biomarkers for early diagnosis of breast cancer remains an important goal. Changes in the… Expand
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2006
2006
PankoMab: a potent new generation anti-tumour MUC1 antibody
Recently, we described a new carbohydrate-induced conformational tumour-epitope on mucin-1 (MUC1) with the potential for… Expand
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Highly Cited
2003
Highly Cited
2003
A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform
There are a large number of stable pancreatic ductal carcinoma cell lines that are used by researchers worldwide. Detailed data… Expand
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Highly Cited
2001
Highly Cited
2001
Human endometrial mucin MUC1 is up-regulated by progesterone and down-regulated in vitro by the human blastocyst.
Expression of MUC1 in endometrial epithelium has been suggested to create a barrier to embryo attachment that must be lifted at… Expand
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Highly Cited
2000
Highly Cited
2000
Reactivity of natural and induced human antibodies to MUC1 mucin with MUC1 peptides and n-acetylgalactosamine (GalNAc) peptides.
Antibodies (Abs) to MUC1 occur naturally in both healthy subjects and cancer patients and can be induced by MUC1 peptide… Expand
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Highly Cited
1997
Highly Cited
1997
Oligosaccharides expressed on MUC1 produced by pancreatic and colon tumor cell lines.
MUC1 is expressed at the apical surface of ductal epithelia of tissues, including breast, pancreas, airway, and the… Expand
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1996
1996
Characterization of apomucin expression in intrahepatic cholangiocarcinomas and their precursor lesions: an immunohistochemical study.
To date, seven apomucins have been characterized and their expression in malignant and premalignant lesions is under evaluation… Expand
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