Tmax

Known as: Time of CMAX, Time to Maximum Concentration, Time to Peak Concentration 
The time it takes to reach the maximum concentration (Cmax) of an exogenous compound or drug in the plasma or a tissue after a dose is administered.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND AND PURPOSE Many perfusion-related MRI parameters are used to investigate the penumbra in stroke. Although time-to… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND AND PURPOSE We sought to assess whether the volume of the ischemic penumbra can be estimated more accurately by… (More)
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2009
2009
BACKGROUND While stable xenon CT (Xe-CT) cerebral blood flow (CBF) is an accepted standard for quantitative assessment of… (More)
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Highly Cited
2006
Highly Cited
2006
To investigate the influence of food and administration of an antacid (aluminum-magnesium hydroxide) or ranitidine on the… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND The pharmacokinetic parameters of four different routes of administration of a single dose of 400 microg of… (More)
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Highly Cited
1999
Highly Cited
1999
Aptamers are oligonucleotide ligands selected, in vitro, to bind a specified target protein. The first aptamer to reach human… (More)
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Highly Cited
1999
Highly Cited
1999
OBJECTIVE We sought to evaluate the pharmacokinetics of subcutaneously administered enoxaparin sodium during and after pregnancy… (More)
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1999
1999
PURPOSE The aim of this study was to determine the effects of a 4-wk individualized training program using Vmax as the exercise… (More)
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Highly Cited
1993
Highly Cited
1993
BACKGROUND Dexmedetomidine is an alpha 2 agonist with potential utility in clinical anesthesia for both its sedative and… (More)
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Highly Cited
1973
Highly Cited
1973
As a means of assessing ventricular performance, we analyzed the time-varying ratio of instantaneous pressure, P(t) , to… (More)
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