• Publications
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Bioadhesive polysaccharide in protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivo.
  • Yan Pan, Y. Li, +5 authors F. Cui
  • Chemistry, Medicine
  • International journal of pharmaceutics
  • 5 December 2002
There are many ongoing investigations to improve the oral bioavailability of peptide and protein formulations. Bioadhesive polysaccharide chitosan nanoparticles (CS-NPs) would seem to further enhanceExpand
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Enhanced solubility and stability of PEGylated liposomal paclitaxel: in vitro and in vivo evaluation.
An improved PEGylated liposomal formulation of paclitaxel has been developed with the purpose of improving the solubility of paclitaxel as well as the physicochemical stability of liposome inExpand
  • 309
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Biodegradable nanoparticles loaded with insulin-phospholipid complex for oral delivery: preparation, in vitro characterization and in vivo evaluation.
Biodegradable nanoparticles loaded with insulin-phospholipid complex were prepared by a novel reverse micelle-solvent evaporation method, in which soybean phosphatidylcholine (SPC) was employed toExpand
  • 335
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Preparation and evaluation of paclitaxel-loaded PEGylated immunoliposome.
A sterically stabilized paclitaxel-loaded liposome tailored to target human breast cancer cells was developed, thereby promoting the efficiency of intracellular delivery of paclitaxel throughExpand
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Docetaxel microemulsion for enhanced oral bioavailability: preparation and in vitro and in vivo evaluation.
A microemulsion system of docetaxel was prepared and evaluated for its solubilization capacity and oral bioavailability improvement. Based on a solubility study and pseudo ternary phase diagrams,Expand
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Preparation of stable nitrendipine nanosuspensions using the precipitation-ultrasonication method for enhancement of dissolution and oral bioavailability.
The aim of this study was to prepare and characterize nitrendipine nanosuspensions to enhance the dissolution rate and oral bioavailability of this drug. Nanosuspensions were prepared by theExpand
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Preparation, characterization and biodistribution of the lactone form of 10-hydroxycamptothecin (HCPT)-loaded bovine serum albumin (BSA) nanoparticles.
10-Hydroxycamptothecin (HCPT) is insoluble in both water and physiological acceptable organic solvents and tends to change into its carboxylate form, which shows minimal anticancer activity andExpand
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Solid lipid nanoparticles (SLNs) to improve oral bioavailability of poorly soluble drugs
  • L. Hu, X. Tang, F. Cui
  • Chemistry, Medicine
  • The Journal of pharmacy and pharmacology
  • 1 December 2004
The purpose of this work was to improve the oral bioavailability of poorly soluble drugs by incorporation into solid lipid nanoparticles (SLNs). All‐trans retinoic acid (ATRA) was used as a poorlyExpand
  • 202
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Preparation of insulin loaded PLGA-Hp55 nanoparticles for oral delivery.
The aim of the present work was to investigate the preparation of PLGA nanoparticles (PNP) and PLGA-Hp55 nanoparticles (PHNP) as potential drug carriers for oral insulin delivery. The nanoparticlesExpand
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Antitumor Effect of Paclitaxel-Loaded PEGylated Immunoliposomes Against Human Breast Cancer Cells
PurposeThe antitumor effect of paclitaxel-loaded PEGylated immunoliposome (PILs) was investigated in breast cancer cell lines and the xenograft model.MethodsHerceptin was conjugated toExpand
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