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Timolol

Known as: Timololum, Timololo, (S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol 
A propanolamine derivative and a non-selective beta-adrenergic antagonist with antihypertensive property. Timolol competitively binds to beta-1… 
National Institutes of Health

Related topics

Related topics

41 relations

Broader (3)

Anti-Arrhythmia AgentsAntihypertensive Agentsethanolamine

Narrower (13)

BlocadrenCosoptDuotravGanfort
Bronchial HyperreactivityCongestive heart failureGlaucoma, Open-AngleHeart Diseases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Drug release from starch-acetate microparticles and films with and without incorporated alpha-amylase.
Highly Cited
2002
Highly Cited
2002
Simultaneous determination of eight beta-blockers by gradient high-performance liquid chromatography with combined ultraviolet and fluorescence detection in corneal permeability studies in vitro.
Highly Cited
2001
Highly Cited
2001
Quantitative structure-retention and retention-activity relationships of beta-blocking agents by micellar liquid chromatography.
Highly Cited
1999
Highly Cited
1999
Cost considerations of medical therapy for glaucoma.
Review
1997
Review
1997
Circadian intraocular pressure management with latanoprost: diurnal and nocturnal intraocular pressure reduction and increased uveoscleral outflow.
Highly Cited
1991
Highly Cited
1991
Norepinephrine-induced plasticity and one-trial olfactory learning in neonatal rats.
Highly Cited
1986
Highly Cited
1986
The effect of topical ophthalmic instillation of timolol and betaxolol on lung function in asthmatic subjects.
The propensity of systemic beta-adrenergic blockers to cause bronchoconstriction in patients with reactive airway disease is well… 
Highly Cited
1985
Highly Cited
1985
Timolol and atenolol: relationships between oxidation phenotype, pharmacokinetics and pharmacodynamics.
The pharmacokinetics and pharmacodynamics of atenolol and timolol were studied in six extensive and four poor metabolisers of… 
Highly Cited
1981
Highly Cited
1981
Timolol and epinephrine in primary open angle glaucoma. Transient additive effect.
A randomized, double-blind clinical study was conducted on patients with primary open angle glaucoma to determine whether timolol… 
Highly Cited
1978
Highly Cited
1978
Effect of timolol therapy on outflow facility.
A 14-week course of timolol therapy in 38 eyes with open-angle glaucoma produced a statistically significant drop (6 mm Hg) in… 
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