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Timolol

Known as: Timololum, Timololo, (S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol 
A propanolamine derivative and a non-selective beta-adrenergic antagonist with antihypertensive property. Timolol competitively binds to beta-1… 
National Institutes of Health

Related topics

Related topics

41 relations

Broader (3)

Anti-Arrhythmia AgentsAntihypertensive Agentsethanolamine

Narrower (13)

BlocadrenCosoptDuotravGanfort
Bronchial HyperreactivityCongestive heart failureGlaucoma, Open-AngleHeart Diseases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Hemodynamic long-term effects of timolol at rest and during exercise in essential hypertension.
Sixteen men with previously untreated essential hypertension in WHO stage I have been studied as out-patients. Oxygen consumption… 
Highly Cited
2004
Highly Cited
2004
Drug release from starch-acetate microparticles and films with and without incorporated alpha-amylase.
1996
1996
Solid-phase extraction and derivatisation methods for beta-blockers in human post mortem whole blood, urine and equine urine.
1993
1993
Peptidergic modulation of in situ canine intrinsic cardiac neurons
Highly Cited
1986
Highly Cited
1986
The effect of topical ophthalmic instillation of timolol and betaxolol on lung function in asthmatic subjects.
The propensity of systemic beta-adrenergic blockers to cause bronchoconstriction in patients with reactive airway disease is well… 
Highly Cited
1985
Highly Cited
1985
Inputs from the A1 noradrenergic region to hypothalamic paraventricular neurons in the rat
1983
1983
beta-Adrenergic dependent downregulation of insulin binding in rat adipocytes.
Highly Cited
1981
Highly Cited
1981
Timolol and epinephrine in primary open angle glaucoma. Transient additive effect.
A randomized, double-blind clinical study was conducted on patients with primary open angle glaucoma to determine whether timolol… 
1981
1981
Aqueous humor dynamics in a series of patients with third neuron Horner's syndrome.
Highly Cited
1978
Highly Cited
1978
Effect of timolol therapy on outflow facility.
A 14-week course of timolol therapy in 38 eyes with open-angle glaucoma produced a statistically significant drop (6 mm Hg) in… 
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