Tight Junctions

Known as: Occludens, Zonula, Junctions, Occluding, Zonula Occluden 
Found near the apical surface of cells in simple epithelia. Forms a sealing "gasket" around the cell by the fusion of adjacent cell membranes which… (More)

Topic mentions per year

Topic mentions per year

1950-2017
0500100019502016

Papers overview

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Review
2016
Review
2016
Mucosal surfaces are lined by epithelial cells and provide an important barrier to the flux of antigens from the outside. This… (More)
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Highly Cited
2002
Highly Cited
2002
The tight junction (TJ) and its adhesion molecules, claudins, are responsible for the barrier function of simple epithelia, but… (More)
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Highly Cited
2001
Highly Cited
2001
Penetration of the gut mucosa by pathogens expressing invasion genes is believed to occur mainly through specialized epithelial… (More)
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Highly Cited
1999
Highly Cited
1999
Epithelia permit selective and regulated flux from apical to basolateral surfaces by transcellular passage through cells or… (More)
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Highly Cited
1998
Highly Cited
1998
Occludin is the only known integral membrane protein localizing at tight junctions (TJ), but recent targeted disruption analysis… (More)
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Highly Cited
1998
Highly Cited
1998
The tight junction protein ZO-1 belongs to a family of multidomain proteins known as the membrane-associated guanylate kinase… (More)
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Highly Cited
1993
Highly Cited
1993
Recently, we found that ZO-1, a tight junction-associated protein, was concentrated in the so called isolated adherens junction… (More)
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Highly Cited
1988
Highly Cited
1988
The tight junction (Zonula occludens), a belt-like region of contact between cells of polarized epithelia, serves as a selective… (More)
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Highly Cited
1986
Highly Cited
1986
A tight junction-enriched membrane fraction has been used as immunogen to generate a monoclonal antiserum specific for this… (More)
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Highly Cited
1969
Highly Cited
1969
Certain junctions between ependymal cells, between astrocytes, and between some electrically coupled neurons have heretofore been… (More)
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