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Tight Junctions

Known as: Occludens, Zonula, Junctions, Occluding, Zonula Occluden 
Found near the apical surface of cells in simple epithelia. Forms a sealing "gasket" around the cell by the fusion of adjacent cell membranes which… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
New research points to a possible link between autism spectrum disorder (ASD) and the gut microbiota as many autistic children… Expand
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Highly Cited
2009
Highly Cited
2009
UNLABELLED The role played by the gut in nonalcoholic fatty liver disease (NAFLD) is still a matter of debate, although animal… Expand
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Review
2006
Review
2006
The tight junction is an intracellular junctional structure that mediates adhesion between epithelial cells and is required for… Expand
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Review
2003
Review
2003
A fundamental function of epithelia and endothelia is to separate different compartments within the organism and to regulate the… Expand
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Highly Cited
2002
Highly Cited
2002
The tight junction (TJ) and its adhesion molecules, claudins, are responsible for the barrier function of simple epithelia, but… Expand
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Review
2001
Review
2001
Tight junctions are one mode of cell–cell adhesion in epithelial and endothelial cellular sheets. They act as a primary barrier… Expand
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Highly Cited
2001
Highly Cited
2001
Penetration of the gut mucosa by pathogens expressing invasion genes is believed to occur mainly through specialized epithelial… Expand
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Highly Cited
1998
Highly Cited
1998
Occludin is the only known integral membrane protein localizing at tight junctions (TJ), but recent targeted disruption analysis… Expand
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Highly Cited
1998
Highly Cited
1998
The tight junction protein ZO-1 belongs to a family of multidomain proteins known as the membrane-associated guanylate kinase… Expand
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Highly Cited
1993
Highly Cited
1993
Recently, we found that ZO-1, a tight junction-associated protein, was concentrated in the so called isolated adherens junction… Expand
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