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Thrombocythemia, Essential

Known as: Idiopathic Thrombocythemias, essential thrombocythaemia, Essential thrombocythemia 
A chronic myeloproliferative neoplasm that involves primarily the megakaryocytic lineage. It is characterized by sustained thrombocytosis in the… 
National Institutes of Health

Related topics

Related topics

36 relations
Acute Megakaryocytic LeukemiasBone MarrowBone marrow stem cellChromosome 13q deletion

Broader (1)

Blood Platelet Disorders

Narrower (1)

Thrombocytosis, Autosomal Dominant

Papers overview

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Highly Cited
2011
Highly Cited
2011
NF-κB Essential Modulator (NEMO) Interaction with Linear and Lys-63 Ubiquitin Chains Contributes to NF-κB Activation*
The IκB kinase (IKK) complex acts as a gatekeeper of canonical NF-κB signaling in response to upstream stimulation. IKK… 
Highly Cited
2011
Highly Cited
2011
Disruption of the ASXL1 gene is frequent in primary, post-essential thrombocytosis and post-polycythemia vera myelofibrosis, but not essential thrombocytosis or polycythemia vera: analysis of…
Background The myeloproliferative neoplasms, essential thrombocytosis, polycythemia vera and primary myelofibrosis, share the… 
Highly Cited
2006
Highly Cited
2006
Environmental factors influence on chemical polymorphism of the essential oils of Lychnophora ericoides.
Highly Cited
2005
Highly Cited
2005
When and how to treat essential thrombocythemia.
Essential thrombocythemia is one of the chronic myeloproliferative disorders, a heterogeneous group of diseases involving clonal… 
Review
2002
Review
2002
Clinical and Pathological Criteria for the Diagnosis of Essential Thrombocythemia, Polycythemia Vera, and Idiopathic Myelofibrosis (Agnogenic Myeloid Metaplasia)
A set of clinical and pathological criteria for the diagnosis and staging of Philadelphia chromosome-negative myeloproliferative… 
Highly Cited
1997
Highly Cited
1997
Defective response to thrombopoietin and impaired expression of c‐mpl mRNA of bone marrow cells in congenital amegakaryocytic thrombocytopenia
Congenital amegakaryocytic thrombocytopenia (CAMT) is an uncommon disorder in newborns and infants, characterized by isolated… 
Highly Cited
1992
Highly Cited
1992
Thromboembolic complications in beta thalassemia major.
Thromboembolic complications in beta-thalassemia major have seldom been reported and their association with risk factors such as… 
Highly Cited
1989
Highly Cited
1989
In vivo and in vitro inhibitory effect of α‐interferon on megakaryocyte colony growth in essential thrombocythaemia
Summary Megakaryocyte (MK) colony growth of bone marrow mononuclear non‐adherent cells was evaluated in 28 patients with… 
Review
1986
Review
1986
Essential Thrombocythemia and Leukemic Transformation
Alkylating agents and 32P have been widely employed in the treatment of patients with essential thrombocythemia (ET). During a… 
Highly Cited
1974
Highly Cited
1974
Methyldopa Liver Damage
Twenty patients are described in whom liver damage appeared to be directly related to the administration of methyldopa. Sixteen… 
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