Thrombocythemia, Essential

Known as: Idiopathic Thrombocythemias, essential thrombocythaemia, Essential Thrombocythemia 
A chronic myeloproliferative neoplasm that involves primarily the megakaryocytic lineage. It is characterized by sustained thrombocytosis in the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1936-2017
010020030019362016

Papers overview

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Highly Cited
2014
Highly Cited
2014
Mutations in the calreticulin (CALR) gene were recently discovered in patients with essential thrombocythemia (ET) lacking the… (More)
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Highly Cited
2014
Highly Cited
2014
Patients with essential thrombocythemia may carry JAK2 (V617F), an MPL substitution, or a calreticulin gene (CALR) mutation. We… (More)
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Highly Cited
2009
Highly Cited
2009
High-throughput DNA sequence analysis was used to screen for TET2 mutations in bone marrow-derived DNA from 239 patients with BCR… (More)
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Highly Cited
2007
Highly Cited
2007
JAK2 617V>F mutation occurs in a homozygous state in 25% to 30% of patients with polycythemia vera (PV) and 2% to 4% with… (More)
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Highly Cited
2005
Highly Cited
2005
Polycythemia vera (PV), essential thrombocythemia (ET), and myeloid metaplasia with myelofibrosis (MMM) are clonal disorders… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Human myeloproliferative disorders form a range of clonal haematological malignant diseases, the main members of which… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND We conducted a randomized comparison of hydroxyurea with anagrelide in the treatment of essential thrombocythemia… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Polycythemia vera, essential thrombocythemia, and idiopathic myelofibrosis are clonal myeloproliferative disorders… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE To assess life expectancy and prognostic factors for survival in patients with polycythemia vera and essential… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND Abnormalities in the number and function of platelets may contribute to thromboembolic complications in patients with… (More)
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