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Thioredoxin Reductase (NADPH)

Known as: NADP Thioredoxin Reductase, Thioredoxin Reductase, Reductase, NADP-Thioredoxin 
A FLAVOPROTEIN enzyme that catalyzes the oxidation of THIOREDOXINS to thioredoxin disulfide in the presence of NADP+. It was formerly listed as EC 1… 
National Institutes of Health

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Papers overview

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Review
2014
Review
2014
The thioredoxin antioxidant system.
Highly Cited
2007
Highly Cited
2007
Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide
Arsenic trioxide (ATO) is an effective cancer therapeutic drug for acute promyelocytic leukemia and has potential anticancer… 
Highly Cited
2005
Highly Cited
2005
Thioredoxin Reductase Is Irreversibly Modified by Curcumin
The thioredoxin reductase (TrxR) isoenzymes, TrxR1 in cytosol or nucleus and TrxR2 in mitochondria, are essential mammalian… 
Review
2004
Review
2004
Organoselenium and organotellurium compounds: toxicology and pharmacology.
In the last three decades, the interest in the field of synthesis and reactivity of organoselenium and organotellurium compounds… 
Review
2001
Review
2001
Reactive oxygen species, antioxidants, and the mammalian thioredoxin system.
Review
2000
Review
2000
Physiological functions of thioredoxin and thioredoxin reductase.
Thioredoxin, thioredoxin reductase and NADPH, the thioredoxin system, is ubiquitous from Archea to man. Thioredoxins, with a… 
Review
1999
Review
1999
Antimicrobial properties of allicin from garlic.
Highly Cited
1998
Highly Cited
1998
Human Placenta Thioredoxin Reductase
Human thioredoxin reductase is a pyridine nucleotide-disulfide oxidoreductase closely related to glutathione reductase but… 
Highly Cited
1996
Highly Cited
1996
A new selenoprotein from human lung adenocarcinoma cells: purification, properties, and thioredoxin reductase activity.
We report the isolation and characterization of a new selenoprotein from a human lung adenocarcinoma cell line, NCI-H441. Cells… 
Highly Cited
1982
Highly Cited
1982
Rat liver thioredoxin and thioredoxin reductase: purification and characterization.
A reproducible scheme has been developed for the preparation of rat liver thioredoxin and thioredoxin reductase (EC 1.6.4.5) by… 
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