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Thiobarbiturates

Known as: Thiobarbiturates [Chemical/Ingredient] 
Compounds in which one or more of the ketone groups on the pyrimidine ring of barbituric acid are replaced by thione groups.
National Institutes of Health

Papers overview

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2018
2018
Barbituric and thiobarbituric acid derivatives have become progressively attractive to medicinal chemists due to their wide range… Expand
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2013
2013
The synthesis of novel series of benzofuran derivatives, containing barbitone moiety, 5-[(2/4-substitutedphenyl)(5-substituted-1… Expand
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2011
2011
A novel series of barbiturate and thiobarbiturate analogs of 2-benzoyl-3-methyl-5-oxo-5H-furo[3,2-g]chromene-6-carbaldehydes (3a… Expand
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2008
2008
NAD+‐dependent histone deacetylases (sirtuins) are enzymes that cleave acetyl groups from lysine residues in histones and other… Expand
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Highly Cited
2005
Highly Cited
2005
The present work offers an analysis of the historical development of the discovery and use of barbiturates in the field of… Expand
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Highly Cited
1990
Highly Cited
1990
Twenty-seven patients were referred for evaluation of anaphylaxis after induction of general anesthesia (GA) in which… Expand
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Highly Cited
1989
Highly Cited
1989
In helical strips of dog cerebral, coronary, mesenteric, renal, and femoral arteries, the addition of thiamylal and thiopental… Expand
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1989
1989
In this study the hypothesis was tested that the substituent at the C 2 position of the barbiturate molecule is crucial for the… Expand
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1958
1958
Thiobarbiturates pass into brain more rapidly than do their oxygen analogs. This is probably due to their higher lipid solubility… Expand
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1949
1949
1. In the heart-lung preparation the thiobarbiturates, thiopental and Surital, exhibit only a moderate degree of cardiac toxicity… Expand
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