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Th17 Cells

Known as: TH-17 Cell, TH 17 Cells, Type 17 Helper T Cells 
A subset of helper T-lymphocytes which synthesize and secrete the interleukins (IL), IL-17A, -21 and -22. These cytokines mediate inflammation by… 
National Institutes of Health

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Hematopoietic and Lymphoid TissueLymphoid TissueMicrobiologicalProcess of secretion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells
In two complementary papers, Casanova, Malissen, and collaborators report the discovery of human RLTPR deficiency, the first… 
Review
2013
Review
2013
Ustekinumab in the treatment of psoriatic arthritis: latest findings and clinical potential
Ustekinumab (UST) is a fully human immunoglobulin G1κ (IgG1κ) monoclonal antibody against common sub-unit p40 of interleukin-12… 
Highly Cited
2012
Highly Cited
2012
Immunopathology and Infectious Diseases IL-10 – Producing Regulatory B 10 Cells Ameliorate Collagen-Induced Arthritis via Suppressing Th 17 Cell Generation
From the Department of Pathology and Center of Infection and Immunology* and the Department of Medicine, University of Hong Kong… 
Highly Cited
2011
Highly Cited
2011
Human endothelial cells generate Th17 and regulatory T cells under inflammatory conditions
Organ transplantation represents a unique therapeutic option for irreparable organ dysfunction and rejection of transplants… 
Highly Cited
2011
Highly Cited
2011
Dynamics of Th17 Cells and Their Role in Schistosoma japonicum Infection in C57BL/6 Mice
Background The current knowledge of immunological responses to schistosomiasis, a major tropical helminthic disease, is… 
Highly Cited
2011
Highly Cited
2011
MCAM-expressing CD4(+) T cells in peripheral blood secrete IL-17A and are significantly elevated in inflammatory autoimmune diseases.
Highly Cited
2010
Highly Cited
2010
Th17/Th1 phenotype in demyelinating disease.
Highly Cited
2009
Highly Cited
2009
Intranasal Delivery of Cholera Toxin Induces Th17-Dominated T-Cell Response to Bystander Antigens
Cholera toxin (CT) is a potent vaccine adjuvant, which promotes mucosal immunity to protein antigen given by nasal route. It has… 
Highly Cited
2009
Highly Cited
2009
Fetal BM‐derived mesenchymal stem cells promote the expansion of human Th17 cells, but inhibit the production of Th1 cells
Th type 17 (Th17) cells have been identified as a proinflammatory T‐cell subset. Here, we investigated the regulation of human… 
2008
2008
Phenotype of CD4+ T cell subsets that develop following mouse facial nerve axotomy
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