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Th1/Th2 Differentiation Pathway

Known as: Th1/Th2 Differentiation 
Helper T cells are found in two distinct cell types, Th1 and Th2, distinguished by the cytokines they produce and respond to and the immune responses… 
National Institutes of Health

Related topics

Related topics

27 relations
CD28 wt AlleleCD40 AntigensCD40 Ligand, humanCD40 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Acute nitrogen dioxide (NO2) exposure enhances airway inflammation via modulating Th1/Th2 differentiation and activating JAK-STAT pathway.
2014
2014
Primary Murine CD4+ T Cells Fail to Acquire the Ability to Produce Effector Cytokines When Active Ras Is Present during Th1/Th2 Differentiation
Constitutive Ras signaling has been shown to augment IL-2 production, reverse anergy, and functionally replace many aspects of… 
2014
2014
The effects of lysine specific demethylase 1 on Th1/Th2 differentiation
This study designed to explore the effect of lysine specific demethylase 1(LSD1) on Th1/Th2polarizing development and related… 
2013
2013
An effective vaccination approach augments anti-HIV systemic and vaginal immunity in mice with decreased HIV-1 susceptible α4β7high CD4+ T cells.
HIV-1 preferentially infects activated CD4(+) T cells expressing α4β7 integrin and conventional vaccination approaches non… 
Highly Cited
2005
Highly Cited
2005
Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance.
Although basophils are known to produce interleukin 4 (IL-4), the roles of these cells have been documented only in mice infected… 
2005
2005
Islet-cell antigen-reactive T cells show different expansion rates and Th1/Th2 differentiation in type 1 diabetic patients and healthy controls.
2004
2004
Alloantibody Production is Regulated by CD4+ T Cells' Alloreactive Pathway, Rather Than Precursor Frequency or Th1/Th2 Differentiation
Although CD4+ T cells play an important role in the regulation of allograft rejection, the exact mechanisms by which they operate… 
2003
2003
HmCRIP, a cysteine‐rich intestinal protein, is expressed by an identified regenerating nerve cell
Review
2002
Review
2002
[Role of SOCS/CIS/SSI molecules in Th1/Th2 differentiation and allergic immune disease].
Highly Cited
2000
Highly Cited
2000
CD28, Ox-40, LFA-1, and CD4 Modulation of Th1/Th2 Differentiation Is Directly Dependent on the Dose of Antigen1
The involvement of specific accessory/costimulatory molecules in differentiation to Th1 and Th2 phenotypes is controversial… 
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