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Tetrodotoxin

Known as: Tarichatoxin, TTX, Tetradotoxin 
A neurotoxin with potential analgesic activity. Tetrodotoxin binds to the pores of fast voltage-gated fast sodium channels in nerve cell membranes… 
National Institutes of Health

Related topics

Related topics

28 relations

Narrower (12)

11-deoxytetrodotoxin11-nortetrodotoxin11-oxotetrodotoxin4-epitetrodotoxin

Broader (5)

Fish VenomsLocal AnestheticsMarine ToxinsPoisons
Fishes, PoisonousIn BloodProcess of secretionSodium Channel

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Different responsiveness of excitatory and inhibitory enteric motor neurons in the human esophagus to electrical field stimulation and to nicotine.
To compare electrical field stimulation (EFS) with nicotine in the stimulation of excitatory and inhibitory enteric motoneurons… 
Highly Cited
1999
Highly Cited
1999
Mediators of anaphylaxis but not activated neutrophils augment cholinergic responses of equine small airways.
Neutrophilic inflammation in small airways (SA) and bronchospasm mediated via muscarinic receptors are features of chronic… 
Highly Cited
1994
Highly Cited
1994
Early Afterdepolarization Formation in Cardiac Myocyte:
Early Afterdepolarization Formation, introduction: Early afterdepolarizations (EADs) are among the mechanisms proposed to… 
Highly Cited
1988
Highly Cited
1988
Unmyelinated cutaneous afferent neurons activate two types of excitatory amino acid receptor in the spinal cord of Xenopus laevis embryos
The trunk and tail skin of Xenopus laevis embryos near the time of hatching is innervated by the mechanoreceptive free nerve… 
Highly Cited
1984
Highly Cited
1984
The Effects of Membrane Potential, Extracellular Potassium, and Tetrodotoxin on the Intracellular Sodium Ion Activity of Sheep Cardiac Muscle
The intracellular sodium ion activity was measured using liquid ion-exchange microelectrodes with rapid response times in sheep… 
Highly Cited
1983
Highly Cited
1983
Effect of caffeine on intramembrane charge movement and calcium transients in cut skeletal muscle fibres of the frog
1. The authors have studied the effect of caffeine in subthreshold concentration (0.5 mmol l−1 at 2‐4 °C) on the contraction… 
Highly Cited
1979
Highly Cited
1979
Chloride and sodium influx: a coupled uptake mechanism in the squid giant axon
The squid giant axon was internally dialyzed while the unidirectional fluxes of either Cl or Na were measured. The effects of… 
Highly Cited
1973
Highly Cited
1973
Molecular size of the tetrodotoxin binding site estimated by irradiation inactivation.
MUCH attention has been directed towards the solubilization and subsequent characterization of functional membrane components in… 
Highly Cited
1970
Highly Cited
1970
Effects of Ca removal on the smooth muscle of the guinea‐pig taenia coli
1. The effects of removing the external Ca ions on the spontaneous and evoked activity of the smooth muscle of the guinea‐pig… 
Highly Cited
1965
Highly Cited
1965
Insensitivity of cultured chick heart cells to autonomic agents and tetrodotoxin.
Trypsin-dispersed cells from heart (ventricles) of 7- to 8-day chick embryos and 6-day posthatched chicks were cultured 2–15 days… 
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