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Tetrodotoxin

Known as: Tarichatoxin, TTX, Tetradotoxin 
A neurotoxin with potential analgesic activity. Tetrodotoxin binds to the pores of fast voltage-gated fast sodium channels in nerve cell membranes… Expand
National Institutes of Health

Papers overview

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Highly Cited
1999
Highly Cited
1999
Many damage-sensing neurons express tetrodotoxin (TTX)-resistant voltage-gated sodium channels. Here we examined the role of the… Expand
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Highly Cited
1997
Highly Cited
1997
Clinical and experimental studies have shown that spinal sensory neurons become hyperexcitable after axonal injury, and… Expand
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Highly Cited
1996
Highly Cited
1996
DORSAL root ganglion sensory neurons associated with C-fibres, many of which are activated by tissue-damage, express an unusual… Expand
Highly Cited
1996
Highly Cited
1996
Sensitization of primary afferent neurons underlies much of the pain and tenderness associated with tissue injury and… Expand
Highly Cited
1992
Highly Cited
1992
The principal voltage-sensitive sodium channel from human heart has been cloned, sequenced, and functionally expressed. The cDNA… Expand
Highly Cited
1992
Highly Cited
1992
Increased activity of dopamine-containing neurons in the ventral tegmental area is necessary for the reinforcing effects of… Expand
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Highly Cited
1988
Highly Cited
1988
In the adult mammalian visual system, ganglion cell axons from the two eyes are segregated from each other into separate layers… Expand
Highly Cited
1980
Highly Cited
1980
1. Intradendritic recordings from Purkinje cells in vitro indicate that white matter stimulation produces large synaptic… Expand
Highly Cited
1968
Highly Cited
1968
1. The hypothesis is put forward that a residue of the ‘active calcium’ which enters the terminal axon membrane during the nerve… Expand
Highly Cited
1964
Highly Cited
1964
Previous studies suggested that tetrodotoxin, a poison from the puffer fish, blocks conduction of nerve and muscle through its… Expand
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