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Testicular Intratubular Germ Cell Neoplasia, Unclassified

Known as: Testicular Intraepithelial Neoplasia, Gonocytoma In Situ, Testicular Intratubular Germ Cell Neoplasia of Unclassified Type 
A non-invasive lesion of the testis, characterized by the presence of malignant large germ cells with abundant cytoplasm in the seminiferous tubules… 
National Institutes of Health

Related topics

Related topics

32 relations
AneuploidyChildhood Testicular Embryonal CarcinomaChildhood Testicular Mixed Embryonal Carcinoma and TeratomaChoriocarcinoma of the Testis

Papers overview

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Highly Cited
2008
Highly Cited
2008
Global DNA hypomethylation in intratubular germ cell neoplasia and seminoma, but not in nonseminomatous male germ cell tumors
Alterations in methylation of CpG dinucleotides at the 5 position of deoxycytidine residues (5mC) are a hallmark of cancer cells… 
Highly Cited
2008
Highly Cited
2008
Clinicopathologic, histologic, and toxicologic findings in 70 cats inadvertently exposed to pet food contaminated with melamine and cyanuric acid.
OBJECTIVE To document clinicopathologic, histologic, and toxicologic findings in cats inadvertently exposed to pet food… 
Highly Cited
2007
Highly Cited
2007
Diagnosis of contralateral testicular intraepithelial neoplasia (TIN) in patients with testicular germ cell cancer: systematic two-site biopsies are more sensitive than a single random biopsy.
Highly Cited
2006
Highly Cited
2006
Spontaneous Regression of Testicular Germ Cell Tumors: An Analysis of 42 Cases
Spontaneous regression of testicular germ cell tumors (GCTs) is a well-recognized phenomenon but has been incompletely… 
Review
2005
Review
2005
Origins and molecular biology of testicular germ cell tumors
Testicular germ cell tumors can be divided into three groups (infantile/prepubertal, adolescent/young adult and spermatocytic… 
Highly Cited
2004
Highly Cited
2004
OCT4: A sensitive and specific biomarker for intratubular germ cell neoplasia of the testis.
PURPOSE OCT4 (POU5F1, OCT3) immunostaining highlights pluripotent cells (embryonal carcinoma and seminoma) in primary testicular… 
Highly Cited
2003
Highly Cited
2003
Radiotherapy with 16 Gy may fail to eradicate testicular intraepithelial neoplasia: preliminary communication of a dose-reduction trial of the German Testicular Cancer Study Group
Low-dose radiotherapy to the testis is effective in eradicating testicular intraepithelial neoplasia (TIN, carcinoma in situ of… 
Highly Cited
2003
Highly Cited
2003
Frozen section analysis-guided organ-sparing approach in testicular tumors: technique, feasibility, and long-term results.
Highly Cited
2001
Highly Cited
2001
Organ sparing surgery for malignant germ cell tumor of the testis.
Highly Cited
1996
Highly Cited
1996
Prevalence of contralateral testicular intraepithelial neoplasia in patients with testicular germ cell neoplasms.
PURPOSE Testicular intraepithelial neoplasia ([TIN], so-called carcinoma in situ of the testis) is hypothesized to be the… 
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