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Tauopathies

Known as: Tauopathies [Disease/Finding], Tauopathy 
Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain… 
National Institutes of Health

Related topics

Related topics

9 relations
DementiaIn BloodMicrobiologicalNeurofibrillary degeneration (morphologic abnormality)

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Comparison of New Tau PET-Tracer Candidates With [18F]T808 and [18F]T807
Early clinical results of two tau tracers, [18F]T808 and [18F]T807, have recently been reported. In the present study, the… 
Review
2010
Review
2010
Nervous yeast: modeling neurotoxic cell death.
Review
2010
Review
2010
Transgenic mouse models of tauopathy in drug discovery.
Tauopathies, including Alzheimer's disease, are neurodegenerative diseases characterized by the deposition of hyperphosphorylated… 
Review
2009
Review
2009
Tau-focused immunotherapy for Alzheimer's disease and related tauopathies.
Immunotherapies targeting the amyloid-beta (Abeta) peptide in Alzheimer's disease (AD) have consistently been effective in mouse… 
Highly Cited
2009
Highly Cited
2009
Association of MAPT haplotype-tagging SNPs with sporadic Parkinson's disease
Highly Cited
2007
Highly Cited
2007
Phenotypic associations of tau and ApoE in Parkinson's disease
Review
2005
Review
2005
The ubiquitin-proteasome system and neurodegenerative disorders.
As in all other mammalian tissues, the UPS (ubiquitin-proteasome system) is fundamental to normal brain function. A consistent… 
2005
2005
Interaction between tau and alpha-synuclein proteins is impaired in the presence of P301L tau mutation.
2000
2000
Molecular classification of the dementias
Highly Cited
1999
Highly Cited
1999
Frequency of tau mutations in three series of non‐Alzheimer's degenerative dementia
Splice‐site and missense mutations have been identified in tau associated with frontotemporal dementia with parkinsonism linked… 
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