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Neurofibrillary degeneration (morphologic abnormality)

Known as: NFT, Neurofibrillary tangles, Tangle, Neurofibrillary 
Abnormal structures located in various parts of the brain and composed of dense arrays of paired helical filaments (neurofilaments and microtubules… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Despite continuing debate about the amyloid β‐protein (or Aβ hypothesis, new lines of evidence from laboratories and clinics… Expand
Review
2004
Review
2004
SummaryEighty-three brains obtained at autopsy from nondemented and demented individuals were examined for extracellular amyloid… Expand
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Highly Cited
2003
Highly Cited
2003
The neuropathological correlates of Alzheimer's disease (AD) include amyloid-beta (Abeta) plaques and neurofibrillary tangles. To… Expand
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Review
2002
Review
2002
It has been more than 10 years since it was first proposed that the neurodegeneration in Alzheimer's disease (AD) may be caused… Expand
Review
2000
Review
2000
Inflammation clearly occurs in pathologically vulnerable regions of the Alzheimer's disease (AD) brain, and it does so with the… Expand
Highly Cited
1996
Highly Cited
1996
Recent neuropathologic autopsy studies found that 15 to 25% of elderly demented patients have Lewy bodies (LB) in their brainstem… Expand
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Highly Cited
1992
Highly Cited
1992
We studied the accumulation of neurofibrillary tangles (NFTs) and senile plaques (SPs) in 10 Alzheimer's disease patients who had… Expand
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Highly Cited
1989
Highly Cited
1989
The intraneuronal accumulation of paired helical filaments in the form of neurofibrillary tangles is one hallmark of the brain… Expand
Highly Cited
1986
Highly Cited
1986
A monoclonal antibody to the microtubule-associated protein tau (tau) labeled some neurofibrillary tangles and plaque neurites… Expand
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Highly Cited
1982
Highly Cited
1982
Recent evidence indicates that the nucleus basalis of Meynert, a distinct population of basal forebrain neurons, is a major… Expand