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Talsaclidine

Known as: (3R)-3-(2-Propynyloxy)quinuclidine 
 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The norepinephrine transporter (NET) transports norepinephrine from the synapse into presynaptic neurons, where norepinephrine… Expand
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2009
2009
In functional assay assessments using the five muscarinic receptor subtypes, a second generation of muscarinic M(1)-preferring… Expand
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Review
2007
Review
2007
M1 muscarinic receptors (M1 mAChRs) play a role in an apparent linkage of three major hallmarks of Alzheimer’s disease (AD… Expand
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2004
2004
The beta-amyloid peptides derived by proteolytic cleavage from the amyloid precursor protein (APP) play a major role in the… Expand
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2003
2003
The amyloid p-peptides Aβ40 and Aβ42 are highly amyloidogenic constituents of brain Pamyloid plaques in Alzheimer's disease (AD… Expand
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2002
2002
HeadingAbstractRationale. Muscarinic-acetylcholine receptor agonists are yet to be used clinically for the treatment of Alzheimer… Expand
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2001
2001
In functional pharmacological assays, talsaclidine has been described as a functionally preferential M1 agonist with full… Expand
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2000
2000
Brain amyloid load in Alzheimer's disease (AD) is, at least in genetic forms, associated with overproduction of amyloid beta… Expand
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1999
1999
The purpose of our studies was to determine the effects of muscarinic receptor agonists on conditioned avoidance responding in… Expand
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1997
1997
The aim of the present investigation was to determine the reasons why the muscarinic receptor agonist talsaclidine (WAL 2014 FU… Expand
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