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TXN2 gene

Known as: TRX2, MT-TRX, TXN2 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Detoxification of Mitochondrial Oxidants and Apoptotic Signaling Are Facilitated by Thioredoxin-2 and Peroxiredoxin-3 during Hyperoxic Injury
Mitochondria play a fundamental role in the regulation of cell death during accumulation of oxidants. High concentrations of… 
2014
2014
Glutaredoxin 2 reduces both thioredoxin 2 and thioredoxin 1 and protects cells from apoptosis induced by auranofin and 4-hydroxynonenal.
Abstract Aims: Mitochondrial thioredoxin (Trx) is critical for defense against oxidative stress-induced cell apoptosis. To date… 
2011
2011
CALL FOR PAPERS Mitochondrial Function/Dysfunction in Health and Disease Hypercholesterolemia increases mitochondrial oxidative stress and enhances the MPT response in the porcine myocardium: bene…
CP. Hypercholesterolemia increases mitochondrial oxidative stress and enhances the MPT response in the porcine myocardium: bene… 
2011
2011
The iron-chelating drug triapine causes pronounced mitochondrial thiol redox stress.
2010
2010
Measuring mitochondrial protein thiol redox state.
2008
2008
Identification of thioredoxin-2 as a regulator of the mitochondrial permeability transition.
Thioredoxin-2 (Trx2) is a multifunctional, mitochondria-specific protein, which inhibits cell death. The mitochondrial… 
Highly Cited
2008
Highly Cited
2008
Protective effect of thioredoxins 1 and 2 in retinal ganglion cells after optic nerve transection and oxidative stress.
PURPOSE Oxidative stress has been implicated in retinal ganglion cell (RGC) death pathways after optic nerve transection (ONT… 
2008
2008
Thiol-Independent Action of Mitochondrial Thioredoxin To Support the Urea Cycle of Arginine Biosynthesis in Schizosaccharomyces pombe
ABSTRACT Thioredoxins usually perform a role as a thiol-disulfide oxidoreductase using their active-site cysteines. The fission… 
2007
2007
NMR solution structure of the reduced form of thioredoxin 2 from Saccharomyces cerevisiae
Thioredoxins (Trxs) are ubiquitous heat-stable proteins of molecular mass approximately 12,000 Da that function as dithiol… 
2006
2006
Protection against oxidant-induced apoptosis by mitochondrial thioredoxin in SH-SY5Y neuroblastoma cells.
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