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TUBEROUS SCLEROSIS 1 (disorder)

Known as: TSC1, Tuberous Sclerosis 1 
Tuberous sclerosis mapped to chromosome 9q34 (TSC1 gene).
National Institutes of Health

Related topics

Related topics

31 relations
Attention Deficit DisorderAutistic DisorderAutosomal dominant inheritanceCardiac rhabdomyoma

Broader (1)

Tuberous Sclerosis

Papers overview

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2013
2013
Disruption of TSC1/2 signaling complex reveals a checkpoint governing thymic CD4+CD25+Foxp3+ regulatory T‐cell development in mice
Thymic‐derived CD4+CD25+Foxp3+ natural regulatory T (nTreg) cells are essential for the maintenance of peripheral immune… 
2005
2005
Distinct Allelic Variants of TSC1 and TSC2 in Epilepsy-Associated Cortical Malformations Without Balloon Cells
Epilepsy-associated malformations of cortical development (MCDs) comprise a variety of dysplastic and neoplastic lesions of yet… 
2005
2005
Pas1, a G1 cyclin, regulates amino acid uptake and rescues a delay in G1 arrest in Tsc1 and Tsc2 mutants in Schizosaccharomyces pombe.
Tuberous sclerosis complex is a tumor suppressor syndrome caused by mutations in either the TSC1 or the TSC2 gene. Previous… 
2002
2002
Molecular genetic analysis of chromosome 9 candidate tumor‐suppressor loci in bladder cancer cell lines
Underrepresentation of chromosome 9 is a common finding in bladder cancer. Frequent loss of the whole chromosome suggests the… 
2001
2001
Cells derived from tuberous sclerosis show a prolonged S phase of the cell cycle and increased apoptosis
Abstract Tuberous sclerosis complex (TSC) is a multisystemic disorder characterized by systemic hamartomas. Although the disease… 
1998
1998
Mutations in the TSC1 gene account for a minority of patients with tuberous sclerosis.
Tuberous sclerosis (TSC) is an autosomal dominant disorder characterised by tumour-like malformations (hamartomas) of the brain… 
1998
1998
Comprehensive mutation analysis of TSC1 using two‐dimensional DNA electrophoresis with DGGE
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterised by the development of benign tumors in multiple… 
1997
1997
A 1.7-megabase sequence-ready cosmid contig covering the TSC1 candidate region in 9q34.
The disease gene TSC1 has been genetically mapped to human chromosome region 9q34, in a 4-cM interval between the markers D9S149… 
1995
1995
A 500-kilobase region containing the tuberous sclerosis locus (TSC1) in a 1.7-megabase YAC and cosmid contig.
1993
1993
Physical mapping within the tuberous sclerosis linkage group in region 9q32-q34.
Pulsed-field gel electrophoresis and flow dot-blot analysis have been used to construct a physical map of the q32-q34 region of… 
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