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TSPY1 gene

Known as: cancer/testis antigen 78, CT78, TSPY 
This gene is putatively involved in sperm differentiation and proliferation.
National Institutes of Health

Related topics

Related topics

7 relations
GonadoblastomaTSPY protein, humanTSPY2 geneTSPYL1 gene

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TSPY1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Fetal Sex and RHD Genotyping with Digital PCR Demonstrates Greater Sensitivity than Real-time PCR.
BACKGROUND Noninvasive genotyping of fetal RHD (Rh blood group, D antigen) can prevent the unnecessary administration of… 
Highly Cited
2009
Highly Cited
2009
SRY Gene Increases the Risk of Developing Gonadoblastoma and/or Nontumoral Gonadal Lesions in Turner Syndrome
The presence of Y-chromosome material in patients with dysgenetic gonads increases the risk of gonadal tumors and/or nontumoral… 
Highly Cited
2007
Highly Cited
2007
Structural variation on the short arm of the human Y chromosome: recurrent multigene deletions encompassing Amelogenin Y.
Structural polymorphism is increasingly recognized as a major form of human genome variation, and is particularly prevalent on… 
Review
2004
Review
2004
Sex chromosome phylogenetics indicate a single transition to terrestriality in the guenons (tribe Cercopithecini).
Highly Cited
2004
Highly Cited
2004
TSPY, the Candidate Gonadoblastoma Gene on the Human Y Chromosome, has a Widely Expressed Homologue on the X - Implications for Y Chromosome Evolution
TSPY, a candidate gene for a factor that promotes gonadoblastoma formation (GBY), is a testis-specific multicopy gene family in… 
1999
1999
Detection of TSPY protein in a unilateral microscopic gonadoblastoma of a Turner mosaic patient with a Y‐derived marker chromosome
Gonadoblastomas are seen almost exclusively in dysgenetic gonads of patients with a chromosomal mosaicism of 45,X and an… 
Review
1998
Review
1998
Structure and function of TSPY, the Y-chromosome gene coding for the “testis-specific protein”
The TSPY genes are arranged in clusters on the Y chromosome of many mammalian species. TSPY is believed to function in early… 
1998
1998
Rodent Y chromosome TSPY gene is functional in rat and non-functional in mouse.
Recombination is believed to prevent genetic deterioration in sexual populations because it allows conservation of functional… 
Highly Cited
1993
Highly Cited
1993
TSPY-related sequences represent a microheterogeneous gene family organized as constitutive elements in DYZ5 tandem repeat units on the human Y chromosome.
TSPY (testis-specific protein, Y-encoded) is encoded by members of a Y-chromosome-specific sequence family. We show here that… 
Highly Cited
1991
Highly Cited
1991
Cloning and sequence analysis of a human Y-chromosome-derived, testicular cDNA, TSPY.
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