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Spermatogenesis is a complex developmental process that ultimately generates mature spermatozoa. This process involves a phase of… Expand We have previously reported a gene expression signature that is a powerful predictor of poor clinical outcome in breast cancer… Expand Structural polymorphism is increasingly recognized as a major form of human genome variation, and is particularly prevalent on… Expand BackgroundOvarian germ cell tumours (OGCTs) typically arise in young females and their pathogenesis remains poorly understood. We… Expand The incidence of melanoma is increasing rapidly, with advanced lesions generally failing to respond to conventional chemotherapy… Expand Carcinoma in situ (CIS) is the precursor of malignant testicular germ cell tumors (GCTs) of adolescents and young adults, being… Expand DNA methylation and copy number in the genomes of three immortalized prostate epithelial and five cancer cell lines (LNCaP, PC3… Expand PURPOSE
We hypothesized that alterations in Y chromosome gene expression may be associated with prostate cancer. To test this… Expand Rapid advances in positional cloning studies have identified most of the genes on the human Y chromosome, thereby providing… Expand TSPY (testis-specific protein, Y-encoded) is encoded by members of a Y-chromosome-specific sequence family. We show here that… Expand