TSC1 gene

Known as: LAM, tuberous sclerosis 1, Tuberous Sclerosis 1 Gene 
This gene is involved in cell cycle regulation and the loss of cellular adhesion.
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
Timothy syndrome CACNA1C 60–80% Unknown 24 Tuberous sclerosis TSC1 and TSC2 20% ~1% 110 The rates quoted in the table depend on… (More)
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Highly Cited
2007
Highly Cited
2007
TNFalpha has recently emerged as a regulator linking inflammation to cancer pathogenesis, but the detailed cellular and molecular… (More)
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Highly Cited
2006
Highly Cited
2006
Tuberous sclerosis complex (TSC) is an autosomal dominant disease characterized by hamartoma formation in various organs. Two… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Tuberous Sclerosis Complex (TSC) is a genetic disorder that occurs through the loss of heterozygosity of either TSC1… (More)
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Highly Cited
2002
Highly Cited
2002
Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder that occurs upon mutation of either the TSC1 or TSC2… (More)
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Highly Cited
2000
Highly Cited
2000
We report here that overexpression of the tuberous sclerosis-1 (TSC1) gene product hamartin results in the inhibition of growth… (More)
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Highly Cited
2000
Highly Cited
2000
Loss of the tumour-suppressor gene TSC1 is responsible for hamartoma development in tuberous sclerosis complex (TSC), which… (More)
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Highly Cited
1998
Highly Cited
1998
Tuberous sclerosis (TSC) is an autosomal dominant disorder caused by a mutation in either the TSC1 or TSC2 tumour suppressor gene… (More)
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Highly Cited
1998
Highly Cited
1998
Tuberous sclerosis is an inherited syndrome associated with mutations in two tumor suppressor genes: TSC1 and TSC2. Tuberin, the… (More)
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Highly Cited
1997
Highly Cited
1997
Tuberous sclerosis (TSC) is an autosomal dominant disorder characterised by the development of hamartomatous growths in many… (More)
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