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TRPM8 gene

Known as: TRPM8, transient receptor potential cation channel subfamily M member 8, CMR1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Inflammatory Effects of Menthol vs. Non-menthol Cigarette Smoke Extract on Human Lung Epithelial Cells: A Double-Hit on TRPM8 by Reactive Oxygen Species and Menthol
Clinical studies suggest that smokers with chronic obstructive pulmonary disease who use menthol cigarettes may display more… 
2014
2014
Identification of a novel 2-pyridyl-benzensulfonamide derivative, RQ-00203078, as a selective and orally active TRPM8 antagonist.
2013
2013
Enhanced insulin clearance in mice lacking TRPM8 channels.
Blood glucose concentration is tightly regulated by the rate of insulin secretion and clearance, a process partially controlled… 
2010
2010
5-benzyloxytryptamine as an antagonist of TRPM8.
2009
2009
Androgen regulated TRPM8 expression: a potential mRNA marker for metastatic prostate cancer detection in body fluids.
Identification of sensitive and specific biomarkers for early detection and prognosis of prostate cancer is essential for timely… 
Highly Cited
2007
Highly Cited
2007
TRPM8-independent Menthol-induced Ca2+ Release from Endoplasmic Reticulum and Golgi*
Menthol, a secondary alcohol produced by the peppermint herb, Mentha piperita, is widely used in the food and pharmaceutical… 
2007
2007
TRPM8 Axonal expression is decreased in painful human teeth with irreversible pulpitis and cold hyperalgesia.
2007
2007
The Transmembrane Segment S6 Determines Cation versus Anion Selectivity of TRPM2 and TRPM8*
TRPM2 and TRPM8, closely related members of the transient receptor potential (TRP) family, are cation channels activated by quite… 
Highly Cited
2006
Highly Cited
2006
The Cold and Menthol Receptor TRPM8 Contains a Functionally Important Double Cysteine Motif*
We have investigated the glycosylation, disulfide bonding, and subunit structure of mouse TRPM8. To do this, amino-terminal c-myc… 
2006
2006
Molecular identification and functional characterization of a temperature-sensitive transient receptor potential channel (TRPM8) from canine.
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