Author pages are created from data sourced from our academic publisher partnerships and public sources.
Top 100 relevant results, sorted by most influential
HSP70 and other possible heat shock or oxidative stress proteins are induced in skeletal muscle, heart, and liver during exercise.
Exercise causes heat shock (muscle temperatures of up to 45 degrees C, core temperatures of up to 44 degrees C) and oxidative stress (generation of O2- and H2O2), and exercise training promotes… Expand
Endurance training affects lactate clearance, not lactate production.
Primed-continuous infusion of [2-3H]- and [U-14C]lactate was used to study the effects of endurance training (running 2 h/day at 29.4 m/min up a 15% gradient) on lactate metabolism in rats.… Expand
Stimulus-dependent modulation of [(3)H]norepinephrine release from rat neocortical slices by gabapentin and pregabalin.
- D. Dooley, C. Donovan, T. Pugsley
- Medicine, Chemistry
- The Journal of pharmacology and experimental…
- 1 December 2000
Gabapentin (GBP; Neurontin) has proven efficacy in several neurological and psychiatric disorders yet its mechanism of action remains elusive. This drug, and the related compounds pregabalin [PGB;… Expand
Sweet talk in the brain: Glucosensing, neural networks, and hypoglycemic counterregulation
Glucose is the primary fuel for the vast majority of cells, and animals have evolved essential cellular, autonomic, endocrine, and behavioral measures to counteract both hypo- and hyperglycemia. A… Expand
Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia.
We sought to elucidate the role of the portal vein afferents in the sympathetic response to hypoglycemia. Laparotomy was performed on 27 male Wistar rats. Portal veins were painted with either 90%… Expand
Importance of Hepatic Glucoreceptors in Sympathoadrenal Response to Hypoglycemia
To ascertain whether hepatic glucoreceptors are important to hypoglycemic counterregulation, a localized euglycemic clamp was employed across the liver during general hypoglycemia. Dogs were infused… Expand
Quantitative assessment of pathways for lactate disposal in skeletal muscle fiber types.
Quantifying the contribution of the various skeletal muscle fiber types toward lactate disposal has proven elusive. In part, this can be attributed to the lack of adequate preparations for the study… Expand
Muscular efficiency during steady-rate exercise. II. Effects of walking speed and work rate.
A comparison of walking against vertical (gradient) and horizontal (trailing weight) forces was made during steady-rate exercise at 0.250, 500, and 750 kg-m/min with speeds of 3,0, 4.5, and 6.0 km/h.… Expand
Inheritance of selected pathotoxin resistance in maize plants regenerated from cell cultures.
- B. G. Gengenbach, C. Green, C. Donovan
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 1 November 1977
Texas male-sterile cytoplasm (cms-T) maize is susceptible to Helminthosporium maydis race T and its pathotoxin, whereas nonsterile cytoplasm maize is resistant. Callus cultures initiated from… Expand
Novel Glucosensor for Hypoglycemic Detection Localized to the Portal Vein
In this investigation, we sought to constrain the locus of essential portohepatic glucosensors and test the hypothesis that they reside strictly in the portal vein and not the liver. Male Wistar rats… Expand