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TRPM7 gene

Known as: CHAK1, TRANSIENT RECEPTOR POTENTIAL-PHOSPHOLIPASE C-INTERACTING KINASE, LONG TRANSIENT RECEPTOR POTENTIAL CHANNEL 7 
This gene plays a role in both ion transport and protein phosphorylation.
National Institutes of Health

Related topics

Related topics

13 relations
CYP19A1 geneHomo sapiensIonophore activityLigand Binding

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TRPM7 wt Allele

Papers overview

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2019
2019
TRPM7 is involved in acid‐induced necrotic cell death in a manner sensitive to progesterone in human cervical cancer cells
Because intravaginal pH is strongly acidic, it is important to investigate the effects of acidosis on cervical cancer cells… 
2018
2018
TRPM7 Regulates AKT/FOXO1–Dependent Tumor Growth and Is an Independent Prognostic Indicator in Renal Cell Carcinoma
Transient receptor potential melastatin 7 (TRPM7) is important for the tumorigenesis and progression of several cancers. However… 
2013
2013
TRPM7 Is Essential for RANKL-Induced Osteoclastogenesis
The transient receptor potential melastatin type 7 (TRPM7) channel is a widely expressed non-selective cation channel with fusion… 
Review
2012
Review
2012
Current understanding of TRPM7 pharmacology and drug development for stroke
The initial excitement and countles efforts to find a pharmacological agent that disrupts the excitotoxic pathway of ischemic… 
Review
2012
Review
2012
Canaux cationiques TRP dans le cancer du sein : expression, rôle et corrélation avec des paramètres cliniques
Breast cancer (BC) has the highest incidence rate in women in industrialized countries. Statistically, it is estimated that one… 
2012
2012
Retrovirus-mediated siRNA targeting TRPM7 gene induces apoptosis in RBL-2H3 cells.
BACKGROUND AND OBJECTIVE Calcium signaling is important for both normal physiologic processes and pathology of various diseases… 
2012
2012
Differential effects of cyclosporin A and tacrolimus on magnesium influx in Caco2 cells.
PURPOSE Hypomagnesemia with urinary magnesium (Mg) wasting is a well acknowledged side effect of cyclosporin A (CsA) and… 
2008
2008
Proton Conductivity through the Human TRPM7 Channel and Its Molecular Determinants*
TRPM7 is a divalent cation-permeable channel that is ubiquitously expressed. Recently, mouse TRPM7 has been shown to be sensitive… 
2008
2008
Molecular determinants of sensitivity and conductivity of human TRPM7 to Mg2+ and Ca2+
It is known that extracellular Mg2+ and Ca2+ can permeate TRPM7 and at the same time block the permeation by monovalent cations… 
2008
2008
Na+-independent Mg2+ transport sensitive to 2-aminoethoxydiphenyl borate (2-APB) in vascular smooth muscle cells: involvement of TRPM-like channels
Magnesium is associated with several important cardiovascular diseases. There is an accumulating body of evidence verifying the… 
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