TRPM7 gene

Known as: CHAK1, TRANSIENT RECEPTOR POTENTIAL-PHOSPHOLIPASE C-INTERACTING KINASE, LONG TRANSIENT RECEPTOR POTENTIAL CHANNEL 7 
This gene plays a role in both ion transport and protein phosphorylation.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
TRPM7 encodes a Ca2+-permeable nonselective cation channel with kinase activity. TRPM7 has been implicated in control of cell… (More)
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Highly Cited
2010
Highly Cited
2010
RATIONALE Cardiac fibrosis contributes to pathogenesis of atrial fibrillation (AF), which is the most commonly sustained… (More)
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Highly Cited
2010
Highly Cited
2010
Mg(2+) is the second-most abundant cation in animal cells and is an essential cofactor in numerous enzymatic reactions. The… (More)
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Highly Cited
2009
Highly Cited
2009
Cardiac arrest victims may experience transient brain hypoperfusion leading to delayed death of hippocampal CA1 neurons and… (More)
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Highly Cited
2006
Highly Cited
2006
TRPM6 and TRPM7 are two known channel kinases that play important roles in various physiological processes, including Mg2… (More)
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Highly Cited
2006
Highly Cited
2006
m-Calpain is a protease implicated in the control of cell adhesion through focal adhesion disassembly. The mechanism by which the… (More)
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Highly Cited
2005
Highly Cited
2005
TRPM7 and its closest homologue, TRPM6, are the only known fusions of an ion channel pore with a kinase domain. Deletion of TRPM7… (More)
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Highly Cited
2003
Highly Cited
2003
TRPM7 is a polypeptide with intrinsic ion channel and protein kinase domains whose targeted deletion causes cells to experience… (More)
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Highly Cited
2003
Highly Cited
2003
Excitotoxicity in brain ischemia triggers neuronal death and neurological disability, and yet these are not prevented by… (More)
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Highly Cited
2003
Highly Cited
2003
Trace metal ions such as Zn(2+), Fe(2+), Cu(2+), Mn(2+), and Co(2+) are required cofactors for many essential cellular enzymes… (More)
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