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TRPM5 gene

Known as: LTRPC5, LONG TRANSIENT RECEPTOR POTENTIAL CHANNEL 5, Transient Receptor Potential Cation Channel, Subfamily M, Member 5 Gene 
This gene is involved in the regulation of cellular calcium flux.
National Institutes of Health

Related topics

Related topics

6 relations
Homo sapiensIonophore activityLigand BindingMolecular Transport

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Expression of sweet taste receptor and gut hormone secretion in modelled type 2 diabetes.
2015
2015
Cholinergic chemosensory cells of the thymic medulla express the bitter receptor Tas2r131.
Review
2013
Review
2013
TRP channels as targets for therapeutic intervention in obesity: focus on TRPV1 and TRPM5.
The disease of obesity is one of the greatest healthcare challenges of our time. The increasing urgency for effective treatment… 
Highly Cited
2013
Highly Cited
2013
TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells
Mucin 5AC (MUC5AC) is secreted by goblet cells of the respiratory tract and, surprisingly, also expressed de novo in mucus… 
Highly Cited
2010
Highly Cited
2010
New frontiers in gut nutrient sensor research: luminal glutamate-sensing cells in rat gastric mucosa.
Dietary free glutamate is known to elicit umami, one of the five basic tastes perceived via the specific taste sensor cells on… 
2008
2008
Quantitative assessment of TRPM5-dependent oral aversiveness of pharmaceuticals using a mouse brief-access taste aversion assay
Many orally administered pharmaceuticals are regarded by humans as aversive, most often described as ‘bitter’. Taste aversiveness… 
2007
2007
Transient receptor potential channel M5 and phospholipaseC-&bgr;2 colocalizing in zebrafish taste receptor cells
In mammals, transient receptor potential (TRP) channel M5 (TRPM5) is coexpressed with phospholipaseC-&bgr;2 (PLC-&bgr;2) in the… 
Highly Cited
2006
Highly Cited
2006
Arachidonic acid can function as a signaling modulator by activating the TRPM5 cation channel in taste receptor cells.
2006
2006
Taste receptor cells express voltage-dependent potassium channels in a cell age-specific manner.
Two voltage-dependent potassium channels, KCNQ1 and KCNH2, are expressed in the taste buds and were identified as strong… 
Review
2006
Review
2006
Thermal Gating of TRP Ion Channels: Food for Thought?
  • E. Liman
  • Science's STKE
  • 2006
  • Corpus ID: 6075630
Members of the family of transient receptor potential (TRP) ion channels mediate a wide range of sensory modalities, including… 
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