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TRK 530

Known as: TRK-530 
National Institutes of Health

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Broader (1)

Diphosphonates

Papers overview

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Review
2008
Review
2008
Pharmacological topics of bone metabolism: a novel bisphosphonate for the treatment of periodontitis.
It has been reported that the pharmacological characteristics of bisphosphonates vary depending on the side chain attached to the… 
Review
2008
Review
2008
Pharmacological topics of bone metabolism. Preface.
This Forum Minireview contains the proceedings of the symposium at the 80th Annual meeting of The Japanese Pharmacological… 
2004
2004
Inhibitory effect of a novel bisphosphonate, TRK-530, on dental calculus formation in rats.
BACKGROUND A newly developed bisphosphonate, TRK-530 (disodium dihydrogen[4-(methylthio)phenylthio]methanebisphosphonate), has… 
Highly Cited
2002
Highly Cited
2002
A novel bisphosphonate inhibits inflammatory bone resorption in a rat osteolysis model with continuous infusion of polyethylene particles
2002
2002
A COMPARATIVE STUDY OF INHIBITORY EFFECTS ON PERI-IMPLANT OSTEOLYSIS BETWEEN ANTI-TNF- ALPHA ANTIBODY AND BISPHOSPHONATE IN A RAT MODEL
  • 2002
  • Corpus ID: 13148379
Introduction; Osteolysis around joint prostheses is reported to be caused by osteoclastic bone resorption, which stimulated by… 
1998
1998
Inhibitory Effects of TRK-530 on Rat Adjuvant Arthritis
TRK-530 is a novel bisphosphonate derivative. We examined the anti-inflammatory effects of TRK-530 on adjuvant arthritis (AA… 
1998
1998
Inhibitory Effect of TRK-530 on Inflammatory Cytokines in Bone Marrow of Rats with Adjuvant Arthritis
TRK-530 is a novel synthetic bisphosphonate compound which exhibits inhibitory activity in the rat adjuvant arthritis (AA) model… 
1998
1998
TRK-530 Inhibits Accumulation of Superoxide Anions Derived from Human Polymorphonuclear Leukocytes and Bone Resorption Induced by Activated Osteoclasts
TRK-530, a newly synthesized bisphosphonate, was assessed for its effects on the accumulation of superoxide anions derived from… 
1997
1997
The effect of TRK-530 on experimental arthritis in mice.
TRK-530 is a newly synthesized diphosphonate derivative. We investigated the effect of TRK-530 on type II collagen-induced… 
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