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TRIM21 protein, human

Known as: tripartite motif-containing 21 protein, human, Ro(SS-A), E3 Ubiquitin-Protein Ligase TRIM21 
E3 ubiquitin-protein ligase TRIM21 (475 aa, ~54 kDa) is encoded by the human TRIM21 gene. This protein is involved in both the mediation of protein… 
National Institutes of Health

Related topics

Related topics

11 relations
Cell Cycle ControlCoiled-Coil DomainEnzyme GeneLigase Gene

Broader (1)

SS-A antigen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Signaling Lymphocyte Activation Molecule Family 5 Enhances Autophagy and Fine-Tunes Cytokine Response in Monocyte-Derived Dendritic Cells via Stabilization of Interferon Regulatory Factor 8
Signaling lymphocyte activation molecule family (SLAMF) receptors are essential regulators of innate and adaptive immune… 
2018
2018
Collusion between neutralizing antibodies and other immune factions in the destruction of adenoviral vectors
Adenoviral vectors hold great promise for gene therapy, the induction of antitumor immunity, and vaccination against viral… 
2016
2016
Brief Report: Patients With Primary Sjögren's Syndrome Who Are Positive for Autoantibodies to Tripartite Motif–Containing Protein 38 Show Greater Disease Severity
Autoantibodies reactive with Ro52 (tripartite motif−containing protein 21 [TRIM21]) are detected in 70% of patients with primary… 
2015
2015
Structure of a TRIM21 - UBE2El complex reveals the specificity of E2 and ubiquitin recognition by TRIM E3 RINGs
TRIM21, a RlNG-containing E3 ubiquitin-ligase of the TRIM   protein family, is a major autoantigen in SLE and Sjogren's syndrome… 
2014
2014
Antibody- and TRIM21-dependent intracellular restriction of Salmonella enterica.
TRIM21 ('tripartite motif-containing protein 21', Ro52) is a ubiquitously expressed cytosolic Fc receptor, which has a potent… 
2013
2013
Estrogen Receptor α Regulates Tripartite Motif–Containing Protein 21 Expression, Contributing to Dysregulated Cytokine Production in Systemic Lupus Erythematosus
To examine the role of 17β‐estradiol in the regulation of the autoantigen tripartite motif–containing protein 21 (TRIM‐21) in… 
2000
2000
Sjoegren’s syndrome(SjS)を合併したlymphomatoid granulomatosis(LyG)の1例
1998
1998
Estrogenic xenobiotics increase expression of SS-A/Ro autoantigens in cultured human epidermal cells.
SS-A/Ro autoantibodies are detected at high levels in patients with autoimmune diseases such as systemic lupus erythematosus. It… 
1993
1993
Sjoegren 症候群を合併したPSSの経過中, 意識障害とけいれんを呈しCTにて両側視床の低吸収域を認めた1例
1988
1988
A case report: Polymyositis(PM) associated with primary biliary cirrhosis(PBC) and Sjoegren's syndrome(SjS).
多発性筋炎(PM)経過観察中,原発性胆汁性肝硬変症(PBC), Sjogren症候群(SjS)を合併した一例を報告する.症例は37歳の女性で,25歳時(昭和42年)に前腕の強直感が出現し,当院整形外科にて慢性関節リウマチの診断を受けた.2… 
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