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TRIM21 gene

Known as: SSA, TRIM21, RNF81 
This gene is involved in the modulation of protein ubiquitination.
National Institutes of Health

Related topics

Related topics

6 relations
Cell Cycle ControlLupus Erythematosus, SystemicTRIM21 protein, humanTRIM34 gene

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TRIM21 wt Allele

Papers overview

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2012
2012
Tyrosine Phosphorylation of the E3 Ubiquitin Ligase TRIM21 Positively Regulates Interaction with IRF3 and Hence TRIM21 Activity
Patients suffering from Systemic Lupus Erythematous (SLE) have elevated type I interferon (IFN) levels which correlate with… 
2011
2011
Anti-Ro52 monoclonal antibodies specific for amino acid 200–239, but not other Ro52 epitopes, induce congenital heart block in a rat model
Background Congenital heart block (CHB) may develop in fetuses of women with anti-Ro/La autoantibodies following placental… 
2005
2005
Autoantibodies against the serotoninergic 5-HT4 receptor and congenital heart block: a reassessment.
2002
2002
Serial analysis of Ro/SSA and La/SSB antibody levels and correlation with clinical disease activity in patients with systemic lupus erythematosus
Objective: To investigate the temporal correlation between anti-Ro/SSA and anti-La/SSB antibody levels and compare them with… 
1999
1999
Protein–Protein Interactions Between Native Ro52 and Immunoglobulin G Heavy Chain
Using a yeast two‐hybrid system to search for proteins interacting with Ro52 autoantigen, we identified a novel protein–protein… 
1994
1994
Epitope mapping of the 52‐kD Ro/SSA autoantigen
Autoantibodies to Ro/SSA are commonly found in sera of patients with systemic lupus erythematosus (SLE) and primary Sjögren's… 
Highly Cited
1990
Highly Cited
1990
Self-regulation of 70-kilodalton heat shock proteins in Saccharomyces cerevisiae
To determine whether the 70-kilodalton heat shock proteins of Saccharomyces cerevisiae play a role in regulating their own… 
Review
1990
Review
1990
Antinuclear antibody profiles in relation to specific disease manifestations of systemic lupus erythematosus
SummaryThe aim of the study was to investigate the prevalence of antinuclear and associated antibodies (anti-dsDNA… 
1989
1989
Comparison of the Directigen 1-2-3 Group A Strep Test with culture for detection of group A beta-hemolytic streptococci
The Directigen 1-2-3 Group A Strep Test (DGAST; BBL Microbiology Systems, Cockeysville, Md.) was compared with conventional… 
Highly Cited
1986
Highly Cited
1986
Evidence of an immunopathogenic basis for central nervous system disease in primary Sjögren's syndrome.
The pathogenesis of central nervous system complications in primary Sjögren's syndrome (CNS-SS) is unknown. In order to determine… 
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