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TRIM21 gene

Known as: SSA, TRIM21, RNF81 
This gene is involved in the modulation of protein ubiquitination.
National Institutes of Health

Related topics

Related topics

6 relations
Cell Cycle ControlLupus Erythematosus, SystemicTRIM21 protein, humanTRIM34 gene

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TRIM21 wt Allele

Papers overview

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Highly Cited
2012
Highly Cited
2012
Association of connexin43 with E3 ubiquitin ligase TRIM21 reveals a mechanism for gap junction phosphodegron control.
Gap junctions (GJs) are sites of direct cell-to-cell communication formed by the connexin (Cx) family of ion channel proteins… 
2011
2011
Anti-Ro52 monoclonal antibodies specific for amino acid 200–239, but not other Ro52 epitopes, induce congenital heart block in a rat model
Background Congenital heart block (CHB) may develop in fetuses of women with anti-Ro/La autoantibodies following placental… 
2005
2005
Autoantibodies against the serotoninergic 5-HT4 receptor and congenital heart block: a reassessment.
Highly Cited
2004
Highly Cited
2004
Evaluation of Multiplexed Fluorescent Microsphere Immunoassay for Detection of Autoantibodies to Nuclear Antigens
ABSTRACT Antibodies to extractable nuclear antigens (ENA) are found in a variety of collagen vascular diseases. Determining the… 
Review
2004
Review
2004
Detection of anti-SSA antibodies by indirect immunofluorescence.
BACKGROUND HEp-2 cells that overexpress the human 60-kDa SSA antigen have been used to improve sensitivity and specificity for… 
2002
2002
Serial analysis of Ro/SSA and La/SSB antibody levels and correlation with clinical disease activity in patients with systemic lupus erythematosus
Objective: To investigate the temporal correlation between anti-Ro/SSA and anti-La/SSB antibody levels and compare them with… 
1999
1999
Protein–Protein Interactions Between Native Ro52 and Immunoglobulin G Heavy Chain
Using a yeast two‐hybrid system to search for proteins interacting with Ro52 autoantigen, we identified a novel protein–protein… 
1994
1994
Epitope mapping of the 52‐kD Ro/SSA autoantigen
Autoantibodies to Ro/SSA are commonly found in sera of patients with systemic lupus erythematosus (SLE) and primary Sjögren's… 
Highly Cited
1990
Highly Cited
1990
Self-regulation of 70-kilodalton heat shock proteins in Saccharomyces cerevisiae
To determine whether the 70-kilodalton heat shock proteins of Saccharomyces cerevisiae play a role in regulating their own… 
Highly Cited
1986
Highly Cited
1986
Evidence of an immunopathogenic basis for central nervous system disease in primary Sjögren's syndrome.
The pathogenesis of central nervous system complications in primary Sjögren's syndrome (CNS-SS) is unknown. In order to determine… 
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