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TREX1 protein, human

Known as: TREX1, 3' Repair Exonuclease 1, 3'-5' Exonuclease TREX1 
Three prime repair exonuclease 1 (369 aa, ~39 kDa) is encoded by the human TREX1 gene. This protein is involved in DNA mismatch repair.
National Institutes of Health

Related topics

Related topics

14 relations
3'-5'-ExonucleasesDNA RepairDNA Repair GeneDNA Replication

Broader (1)

Three Prime Repair Exonuclease 1

Papers overview

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2018
2018
Rad6-Bre1 mediated histone H2Bub1 protects uncapped telomeres from exonuclease Exo1 in Saccharomyces cerevisiae.
2017
2017
AB0001 First description and functional proteomic analysis of a protective for rheumatoid arthritis gene polymorphism
Background Rheumatoid Arthritis (RA) is the most common systemic autoimmune disease, with a respective expanded genetic research1… 
Review
2014
Review
2014
Clearance of endogenous L1 retroelements in the cytosol by TREX1 prevents neuronal toxicity
Author(s): Thomas, Charles Austin | Advisor(s): Muotri, Alysson R | Abstract: This Dissertation is broken into four chapters. In… 
2014
2014
Removing the TREX 1 safety net : oxidized DNA overcomes immune silencing by exonuclease TREX 1
2010
2010
The TREX1 3' exonuclease and autoimmune disease: Structural and biochemical analysis of disease mutants involved in autoimmune dysfunction
The homodimeric TREX1 protein is a member of the DnaQ family of exonucleases and catalyzes the major 3′ exonuclease activity… 
2010
2010
ADAMTS13 dysfunction and a novel frameshift mutation in the TREX1 gene in a patient with Aicardi-Goutières syndrome
Aicardi-Goutieres syndrome (AGS) is a genetic infantile encephalopathy with intracerebral calcifications, leukodystrophy… 
Review
2008
Review
2008
Book reviews
The book can be clearly recommended to those who want to learn about modern methods of molecular genetics and use them in the… 
1998
1998
Lethality of high linear energy transfer cosmic radiation to Escherichia coli DNA repair-deficient mutants during the 'SL-J/FMPT' space experiment.
We investigated the lethal and mutagenic effects of high linear energy transfer cosmic radiation on 11 strains of Escherichia… 
1993
1993
Etude de la regulation post-transcriptionnelle d'une exonuclease chez e. Coli : la polynucleotide phosphorylase
Chez e. Coli, la pnpase, le produit du gene pnp est une exonuclease capable de degrader de facon processive les arnm de 3 en 5… 
1992
1992
Purification andcharacterization ofan endo-exonuclease fromadult flies ofDrosophila melanogaster
An endo-exonuclease (designated nuclease 111) has beenpurified tonearhomogeneity fromadult flies of Drosophila melanogaster… 
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