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TREX1 protein, human

Known as: TREX1, 3' Repair Exonuclease 1, 3'-5' Exonuclease TREX1 
Three prime repair exonuclease 1 (369 aa, ~39 kDa) is encoded by the human TREX1 gene. This protein is involved in DNA mismatch repair.
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Defects of the intracellular enzyme 3′ repair exonuclease 1 (Trex1) cause the rare autoimmune condition Aicardi–Goutières… 
2015
2015
IMPORTANCE Familial chilblain lupus is a rare, autosomal dominant form of lupus erythematosus characterized by cold-induced… 
Highly Cited
2014
Highly Cited
2014
Cytosolic detection of DNA is crucial for the initiation of antiviral immunity but can also cause autoimmunity in the context of… 
2007
2007
TREX1 is the most abundant mammalian 3′ → 5′ DNA exonuclease. It has been described to form part of the SET complex and is… 
Highly Cited
2001
Highly Cited
2001
The excision of nucleotides from DNA 3′ termini is an important step in DNA replication, repair, and recombination pathways to…