Skip to search formSkip to main contentSkip to account menu

TRAF7 gene

Known as: RING FINGER AND WD REPEAT DOMAINS-CONTAINING PROTEIN 1, TNF RECEPTOR-ASSOCIATED FACTOR 7, DKFZp586I021 
This gene is involved in both MAPK signaling and protein ubiquitination.
National Institutes of Health

Related topics

Related topics

3 relations
Positive Regulation of ApoptosisSignal Transduction InductionUbiquitination

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Adenomatoid tumors of the male and female genital tract are defined by TRAF7 mutations that drive aberrant NF-kB pathway activation
Adenomatoid tumors are the most common neoplasm of the epididymis, and histologically similar adenomatoid tumors also commonly… 
Highly Cited
2017
Highly Cited
2017
Progestin-associated shift of meningioma mutational landscape
Background Meningiomas are the most common primary tumor of the central nervous system. The relationship between meningioma and… 
Highly Cited
2016
Highly Cited
2016
Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma.
BACKGROUND Meningiomas are the most common primary intracranial tumor in adults. Identification of SMO and AKT1 mutations in… 
Review
2016
Review
2016
Meningioma Genomics: Diagnostic, Prognostic, and Therapeutic Applications
There has been a recent revolution in our understanding of the genetic factors that drive meningioma, punctuating an equilibrium… 
Review
2014
Review
2014
Atypical meningoma: current management dilemmas and prospective clinical trials
Atypical meningioma is an intermediate grade tumour with a greater risk of recurrence following surgical resection. Changes to… 
Highly Cited
2013
Highly Cited
2013
Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations
Meningiomas are among the most frequent intracranial tumors. The secretory variant of meningioma is characterized by glandular… 
Highly Cited
2011
Highly Cited
2011
TRAF7 Protein Promotes Lys-29-linked Polyubiquitination of IκB Kinase (IKKγ)/NF-κB Essential Modulator (NEMO) and p65/RelA Protein and Represses NF-κB Activation
Tumor necrosis factor receptor-associated factor (TRAF) proteins are cytoplasmic regulatory molecules that function as signal… 
Highly Cited
2005
Highly Cited
2005
The Tumor Suppressor Cylindromatosis (CYLD) Acts as a Negative Regulator for Toll-like Receptor 2 Signaling via Negative Cross-talk with TRAF6 and TRAF7*
Toll-like receptor 2 (TLR2) plays an important role in host defense against bacterial pathogens. Activation of TLR2 signaling not… 
Highly Cited
2005
Highly Cited
2005
TRAF7 sequesters c-Myb to the cytoplasm by stimulating its sumoylation.
Small ubiquitin-related modifiers (SUMOs) are proteins that are posttranslationally conjugated to diverse proteins. The c-myb… 
Highly Cited
2004
Highly Cited
2004
TRAF7 Potentiates MEKK3-induced AP1 and CHOP Activation and Induces Apoptosis*
The tumor necrosis factor receptor-associated factor (TRAF) protein family members are critically involved in activation of NF-κB… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)