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TPMT wt Allele

Known as: TPMT Wild-type Allele, Thiopurine S-Methyltransferase wt Allele, TPMT*1 Allele 
Human TPMT wild-type allele is located in the vicinity of 6p22.3 and is approximately 26 kb in length. This allele, which encodes thiopurine S… 
National Institutes of Health

Related topics

Related topics

5 relations
MethylationNucleotide MetabolismTPMT*2 AlleleThiopurine S methyltranferase deficiency

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Análisis de los polimorfismos génicos de Tiopurina S-Metiltransferasa (TPMT) en pacientes pediátricos mexicanos con cáncer
La Tiopurina S-Metiltransferasa (TPMT) cataliza la S-metilacion de tiopurinas como la 6-mercaptopurina, 6-tioguanina y… 
2011
2011
The frequency and distribution of thiopurine S-methyltransferase alleles in south Iranian population
Thiopurine methyltransferase (TPMT) catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine, 6-thioguanine, and… 
2005
2005
Molecular analysis of the thiopurine S‐methyltransferase alleles in Bolivians and Tibetans
Background:  Thiopurine drugs are used as immunosuppressant or cytotoxic drugs. Thiopurine S‐methyltransferase (TPMT) methylates… 
2003
2003
Genetic determinants of the thiopurine methyltransferase intermediate activity phenotype in British Asians and Caucasians.
Highly Cited
2002
Highly Cited
2002
Molecular analysis of thiopurine S-methyltransferase alleles in South-east Asian populations.
Thiopurine S-methyltransferase (TPMT) catalyses the S-methylation of thiopurine drugs. In Caucasians, four variant TPMT alleles… 
2001
2001
The use of denaturing high-pressure liquid chromatography for the detection of mutations in thiopurine methyltransferase.
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