TPMT*3A Allele

Known as: TPMT, A154T, Y240C, TPMT, c.615G>C, c.874A>G, TPMT-3A Allele 
Human TPMT*3A allele is located in the vicinity of 6p22.3 and is approximately 26 kb in length. This allele, a variant form of the TPMT wild-type… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2013
012320062013

Papers overview

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2013
2013
Thiopurine S-methyltransferase (TPMT) is a key enzyme that deactivates thiopurines, into their inactive metabolite, 6… (More)
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2013
2013
BACKGROUND The genetic polymorphism of thiopurine methyltransferase (TPMT) is well characterized in most populations. Four common… (More)
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2013
2013
BACKGROUND AND AIMS Thiopurine S-methyltransferase (TPMT) is responsible for inactivation of thiopurine drugs which are commonly… (More)
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2010
2010
This study provides the first analysis of the TPMT mutant allele frequency in a sample of the Jordanian population and indicates… (More)
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2006
2006
BACKGROUND AND OBJECTIVE Thiopurine S-methyltransferase (TPMT) metabolizes thiopurine drugs regulating their cytotoxicity and… (More)
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